Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.34 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169849 | 0.87 | NPC1 (0.36) | NPC1RAB9AKDM1AKDM1BMAPT | |
| SCHEMBL16068644 | 0.86 | CUL4A (0.49) | CUL4AGAA | |
| SCHEMBL17466059 | 0.86 | KDM4E (0.42) | NPC1RAB9AKDM1AKDM1BMAPT | |
| SCHEMBL2916569 | 0.82 | AKR1B1 (0.35) | NPC1RAB9ACUL4AAKR1B1LCK | |
| SCHEMBL27828718 | 0.79 | KDM1A (0.39) | NPC1RAB9AKDM1AKDM1BMAPT | |
| SCHEMBL8370837 | 0.78 | NPC1 (0.37) | NPC1RAB9ACUL4AMAPTPOLB | |
| SCHEMBL23706551 | 0.76 | CUL4A (0.40) | NPC1RAB9ACUL4AMAPTPOLB | |
| SCHEMBL27509330 | 0.75 | INPPL1 (0.49) | NPC1RAB9AKDM1AKDM1BMAPT | |
| SCHEMBL31118436 | 0.75 | NPC1 (0.45) | NPC1RAB9AKDM1AKDM1BMAPT | |
| SCHEMBL1223997 | 0.75 | NPC1 (0.45) | NPC1RAB9AKDM1AKDM1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4059747-A | — | — | None | — | — | JP | disclosed |
| JP-H0459747-A | PRODUCTION OF BENZOIC ACID DERIVATIVE AND INTERMEDIATE THEREOF AND PRODUCTION OF THE INTERMEDIATE | NIPPON NOHYAKU CO LTD | 1992-02-26 | — | — | JP | disclosed |