Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9617785 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTKMT2ATDP1MAPT | |
| SCHEMBL9458110 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTKMT2ATDP1MAPT | |
| SCHEMBL9458101 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTKMT2ATDP1MAPT | |
| SCHEMBL20045170 | 0.86 | KMT2A (0.61) | SMN1; SMN2HTTKMT2ATDP1MAPT | |
| SCHEMBL12154218 | 0.86 | KMT2A (0.61) | SMN1; SMN2HTTKMT2ATDP1MAPT | |
| SCHEMBL1895159 | 0.85 | KMT2A (0.53) | SMN1; SMN2HTTKMT2ATDP1MAPT | |
| SCHEMBL8366016 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTKMT2ATDP1MAPT | |
| SCHEMBL9615830 | 0.84 | NPC1 (0.43) | SMN1; SMN2HTTKMT2ATDP1MAPT | |
| SCHEMBL9458580 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTKMT2ATDP1MAPT | |
| SCHEMBL9458587 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTKMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4059745-A | — | — | None | — | — | JP | disclosed |
| JP-H0459745-A | ESTER COMPOUND | SEIKO EPSON CORP | 1992-02-26 | — | — | JP | disclosed |