Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | FSCN1 | Q16658 | 8/20 | 0.63 |
| ▸ | BRD4 | O60885 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9146030 | 0.79 | FSCN1 (0.60) | KDM4ELMNAHPGDALDH1A1MAPT | |
| SCHEMBL18284179 | 0.77 | CNR1 (0.54) | KDM4ELMNAHPGDALDH1A1MAPT | |
| SCHEMBL9974671 | 0.77 | KDM4E (0.59) | KDM4ELMNAALDH1A1FSCN1BRD4 | |
| SCHEMBL12284564 | 0.77 | KDM4E (0.59) | KDM4EALDH1A1BRD4 | |
| SCHEMBL18284226 | 0.76 | HDAC1 (0.48) | KDM4ELMNAHPGDALDH1A1MAPT | |
| SCHEMBL24273311 | 0.74 | NR4A2 (0.67) | KDM4ELMNAALDH1A1MAPTGAA | |
| SCHEMBL1514424 | 0.74 | MAPT (0.63) | KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL30125450 | 0.73 | P2RX3 (0.61) | LMNAMAPTGAAPOLBHTT | |
| SCHEMBL15241737 | 0.73 | BRD4 (0.54) | KDM4ELMNAHPGDALDH1A1MAPT | |
| SCHEMBL18284219 | 0.73 | NR4A2 (0.55) | KDM4ELMNAHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4266874-A | — | — | None | — | — | JP | disclosed |
| JP-H04266874-A | ISOQUINOLONE DERIVATIVE | NISSHIN FLOUR MILLING CO LTD | 1992-09-22 | — | — | JP | disclosed |