Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | PYGM | P11217 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400371 | 0.77 | CYP2C9 (0.43) | CYP2C9CYP2C19MEN1CYP1A2CYP3A4 | |
| SCHEMBL9618018 | 0.73 | CYP1A2 (0.49) | CYP2C9CYP2C19MEN1CYP1A2CYP3A4 | |
| SCHEMBL9422554 | 0.71 | CACNA1F (0.34) | CYP2C9CYP2C19MEN1CYP1A2CYP3A4 | |
| SCHEMBL4756165 | 0.69 | TP53 (0.43) | CYP2C9CYP2C19MEN1CYP1A2CYP3A4 | |
| SCHEMBL9033423 | 0.69 | MAPT (0.42) | CYP2C9CYP2C19MEN1CYP1A2CYP3A4 | |
| SCHEMBL7267495 | 0.68 | CYP2C9 (0.40) | CYP2C9CYP2C19MEN1CYP1A2CYP3A4 | |
| SCHEMBL9033375 | 0.68 | CYP1A2 (0.54) | CYP2C9CYP2C19MEN1CYP1A2CYP3A4 | |
| SCHEMBL9033394 | 0.68 | CYP1A2 (0.54) | CYP2C9CYP2C19MEN1CYP1A2CYP3A4 | |
| SCHEMBL9034242 | 0.68 | CYP1A2 (0.54) | CYP2C9CYP2C19MEN1CYP1A2CYP3A4 | |
| SCHEMBL9032893 | 0.68 | CYP1A2 (0.57) | CYP2C9CYP2C19MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4279566-A | — | — | None | — | — | JP | disclosed |
| JP-H04279566-A | 1,4-DIHYDROPYRIDINE DERIVATIVE | KYOWA HAKKO KOGYO CO LTD | 1992-10-05 | — | — | JP | disclosed |