Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640174 | 0.89 | PTPN11 (0.54) | PTPN11THRATHRBRARBNPC1 | |
| SCHEMBL9641454 | 0.89 | PTPN11 (0.54) | PTPN11THRATHRBRARBNPC1 | |
| SCHEMBL9641122 | 0.89 | PTPN11 (0.54) | PTPN11THRATHRBRARBNPC1 | |
| SCHEMBL9640278 | 0.89 | PTPN11 (0.54) | PTPN11THRATHRBRARBNPC1 | |
| SCHEMBL9641082 | 0.89 | PTPN11 (0.54) | PTPN11THRATHRBRARBNPC1 | |
| SCHEMBL9640668 | 0.87 | PTPN11 (0.52) | PTPN11THRATHRBRARBNPC1 | |
| SCHEMBL9640212 | 0.86 | PTPN11 (0.51) | PTPN11THRATHRBRARBNPC1 | |
| SCHEMBL9808840 | 0.86 | THRA (0.46) | PTPN11THRATHRBRARBNPC1 | |
| SCHEMBL9478567 | 0.85 | RARB (0.52) | PTPN11THRATHRBRARBNPC1 | |
| SCHEMBL8733164 | 0.85 | PTPN11 (0.46) | PTPN11THRATHRBRARBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4082862-A | — | — | None | — | — | JP | disclosed |
| JP-H0482862-A | ANTIFERROELECTRIC LIQUID CRYSTAL COMPOUND | TAKASAGO INTERNATL CORP | 1992-03-16 | — | — | JP | disclosed |