Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811429 | 0.87 | GAA (0.53) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL18878112 | 0.81 | CES2 (0.44) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL524175 | 0.81 | GAA (0.49) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL5629366 | 0.81 | KDM4E (0.63) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL28104177 | 0.81 | KDM4E (0.50) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL3726674 | 0.81 | SOS1 (0.47) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL3723166 | 0.81 | ABL1 (0.47) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL3719012 | 0.81 | GAA (0.45) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL1271994 | 0.80 | KDM4E (0.61) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL20703659 | 0.80 | KDM4E (0.50) | GAAKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4295441-A | — | — | None | — | — | JP | disclosed |
| JP-H04295441-A | COMPOUND HAVING AROMATIC RING | OTSUKA PHARMACEUT CO LTD | 1992-10-20 | — | — | JP | disclosed |