Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402485 | 0.86 | GPR52 (0.61) | GPR52AURKATP53NAMPTRAB9A | |
| SCHEMBL961206 | 0.86 | GPR52 (0.63) | GPR52AURKATP53NAMPTRAB9A | |
| SCHEMBL959859 | 0.85 | GPR52 (0.73) | GPR52AURKATP53NAMPTRAB9A | |
| SCHEMBL12918938 | 0.85 | GPR52 (0.61) | GPR52AURKATP53NAMPTRAB9A | |
| SCHEMBL12918937 | 0.84 | GPR52 (0.59) | GPR52AURKATP53NAMPTRAB9A | |
| Hydrochloric Acid SCHEMBL958163 | 0.84 | GPR52 (0.60) | GPR52AURKATP53NAMPTRAB9A | |
| SCHEMBL959095 | 0.82 | GPR52 (0.59) | GPR52AURKATP53NAMPTRAB9A | |
| SCHEMBL958255 | 0.82 | GPR52 (0.56) | GPR52AURKATP53MMP13ROCK2 | |
| SCHEMBL961439 | 0.81 | GPR52 (0.52) | GPR52AURKATP53RAB9AMMP13 | |
| SCHEMBL961496 | 0.80 | SMYD2 (0.56) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | GPR4, NR3C2, NR5A2 | GPR52 23/4885AURKA 4359/4885SIGMAR1 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.