Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12277785 | 0.82 | TDP1 (0.48) | MC4RBRD4TDP1LMNANPSR1 | |
| SCHEMBL9444404 | 0.77 | BRD4 (0.47) | FLT1CDK8LIMK1ROCK1BRD4 | |
| SCHEMBL13587950 | 0.77 | BRD4 (0.56) | FLT1CDK8CDK9LIMK1ROCK1 | |
| SCHEMBL8190241 | 0.77 | CLK4 (0.49) | FLT1CDK8CDK9LIMK1ROCK1 | |
| SCHEMBL12277425 | 0.76 | CCNE2 (0.42) | FLT1CDK8CDK9LIMK1ROCK1 | |
| SCHEMBL12797931 | 0.73 | FLT1 (0.49) | FLT1CDK8CDK9LIMK1ROCK1 | |
| SCHEMBL27874492 | 0.73 | CLK4 (0.45) | FLT1CDK8CDK9LIMK1ROCK1 | |
| SCHEMBL19353774 | 0.73 | CYP3A4 (0.50) | FLT1CDK8CDK9LIMK1ROCK1 | |
| SCHEMBL12797926 | 0.73 | FLT1 (0.45) | FLT1CDK8CDK9LIMK1ROCK1 | |
| SCHEMBL12797942 | 0.73 | FLT1 (0.42) | FLT1CDK8CDK9LIMK1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483953-A1 | 1-Isopropyl-2-tolylimidazole as an epoxy resin curative | TEXACO CHEMICAL COMPANY (US) | 1992-05-06 | — | — | EP | claimed |
| US-5086155-A | Lengthy pot life at ambient temperatures; stability; resistance to heat, chemicals and moisture | TEXACO CHEMICAL COMPANY (US) | 1992-02-04 | — | — | US | claimed |
| JP-4298524-A | — | — | None | — | — | JP | disclosed |
| US-10043987-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-08-07 | — | — | US | disclosed |
| JP-H04298524-A | EPOXY RESIN COMPOSITION AND ITS CURING METHOD | TEXACO CHEM CO | 1992-10-22 | — | — | JP | disclosed |
| EP-0483953-A1 | 1-Isopropyl-2-tolylimidazole as an epoxy resin curative | TEXACO CHEMICAL COMPANY (US) | 1992-05-06 | — | — | EP | disclosed |
| EP-0483953-A1 | 1-Isopropyl-2-tolylimidazole as an epoxy resin curative | TEXACO CHEMICAL COMPANY (US) | 1992-05-06 | — | — | EP | disclosed |
| EP-0483953-A1 | 1-Isopropyl-2-tolylimidazole as an epoxy resin curative | TEXACO CHEMICAL COMPANY (US) | 1992-05-06 | — | — | EP | disclosed |
| US-5086155-A | Lengthy pot life at ambient temperatures; stability; resistance to heat, chemicals and moisture | TEXACO CHEMICAL COMPANY (US) | 1992-02-04 | — | — | US | disclosed |
| US-5086155-A | Lengthy pot life at ambient temperatures; stability; resistance to heat, chemicals and moisture | TEXACO CHEMICAL COMPANY (US) | 1992-02-04 | — | — | US | disclosed |
| US-5086155-A | Lengthy pot life at ambient temperatures; stability; resistance to heat, chemicals and moisture | TEXACO CHEMICAL COMPANY (US) | 1992-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10043987-B2 | Organic electroluminescent materials and devices | L3MBTL3, LAS1L, LMNB1 | FLT1 3369/4885CDK8 2034/4885CDK9 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.