LMNB1

Lamin-B1 · P20700 · LMNB1 on Sugi Atlas →

0 patent compounds predicted against LMNB1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to LMNB1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria PHASE2COMPLETED
Optimizing IV Gentamicin in JEB PHASE1/PHASE2UNKNOWN
Study to Determine Optimal Dose and Evaluate Safety, Tolerability, and Pharmacokinetics of Progerinin in Patients With Hutchinson-Gilford Progeria Syndrome (HGPS) PHASE2ACTIVE_NOT_RECRUITING
Hearts in Rhythm Organization (HiRO)National Registry and Bio Bank nanENROLLING_BY_INVITATION
Clinical and Genetic Examinations of Dilated Cardiomyopathy nanCOMPLETED
The Deep Phenotype of Lamin A/C Cardiomyopathy nanUNKNOWN
Cardiac Arrhythmias and Sudden Death in Patients Affected With Laminopathies nanUNKNOWN
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH) nanRECRUITING
Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure nanRECRUITING
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING
ASF Alport Patient Registry nanRECRUITING
Genetics of Neonatal Encephalopathy and Related Disorders nanRECRUITING
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes nanRECRUITING
The Classification and Cause of Leukodystrophies of Unknown Cause nanCOMPLETED
Natural History Study of Mitochondrial Myopathy nanRECRUITING
Natural History of the Leukodystrophies nanCOMPLETED
Imaging Genetics of Laryngeal Dystonia nanRECRUITING
Clinical, Structural and Mechanical Features in Patients With Left Bundle Branch Block. nanUNKNOWN
Genotype-phenotype Correlation in Junctional Epidermolysis Bullosa nanUNKNOWN
The Genetics of Cardiomyopathy and Heart Failure nanWITHDRAWN
The Nosology and Etiology of Leukodystrophies of Unknown Causes nanCOMPLETED
Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy nanRECRUITING
The Impact of Mitochondrial Dysfunction on Human Bone Cell Metabolism and Remodelling nanACTIVE_NOT_RECRUITING
LobularCard Trial: Searching for Novel Germline Mutations in Lobular Breast Cancer Patients nanACTIVE_NOT_RECRUITING
Investigations of Juvenile Neuronal Ceroid Lipofuscinosis nanRECRUITING
Dilated Cardiomyopathy-Cardiac Magnetic Resonance (DCM-CMR) Ancillary Study nanACTIVE_NOT_RECRUITING
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk nanNOT_YET_RECRUITING
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
LAMA2 Genetic Correction nanCOMPLETED
Biomarker Research in Inherited Movement Disorders nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a LMNB1 binder may also engage these)

ProteinNameSimilarity
P70615 1.000 P70615 →
P09010 1.000 P09010 →
P14733 1.000 P14733 →
P14731 1.000 P14731 →
P21910 0.995 P21910 →
P13648 0.995 P13648 →
P14732 0.994 P14732 →
P08928 0.993 P08928 →
Q3ZD69 0.993 Q3ZD69 →
Q19289 0.991 Q19289 →
P48679 0.991 P48679 →
P23731 0.991 P23731 →
LMNB2 Lamin-B2 0.991 landscape →
O02365 0.990 O02365 →
P21619 0.990 P21619 →
P10999 0.990 P10999 →
P23730 0.989 P23730 →
P90900 0.989 P90900 →
P11048 0.989 P11048 →
Q03427 0.987 Q03427 →
P48678 0.986 P48678 →
LMNA Prelamin-A/C 0.986 landscape →
Q6P864 0.986 Q6P864 →
Q21065 0.986 Q21065 →
P08727 0.985 P08727 →
P05784 0.985 P05784 →
Q7SY65 0.985 Q7SY65 →
O93256 0.984 O93256 →
P08802 0.984 P08802 →
Q6GQ73 0.984 Q6GQ73 →