Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 8/20 | 0.55 |
| ▸ | QDPR | P09417 | 1/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82406 | 0.94 | SLC18A3 (0.61) | SLC18A3SIGMAR1HTR2CQDPRP2RY14 | |
| Hydrochloric Acid SCHEMBL2803065 | 0.92 | HTR2C (0.61) | SLC18A3SIGMAR1HTR2CQDPRP2RY14 | |
| SCHEMBL17850376 | 0.86 | SLC18A3 (0.53) | SLC18A3SIGMAR1HTR2CQDPRP2RY14 | |
| SCHEMBL15508750 | 0.82 | HTR3A (0.66) | SLC18A3SIGMAR1HTR2CHTR3A | |
| SCHEMBL14544196 | 0.82 | HTR3A (0.66) | SLC18A3SIGMAR1HTR2CHTR3A | |
| Toluene SCHEMBL27818685 | 0.80 | SLC18A3 (0.80) | SLC18A3SIGMAR1HTR2CKMT2A | |
| SCHEMBL12640583 | 0.80 | SLC18A3 (0.55) | SLC18A3SIGMAR1HTR2CQDPRHTR3A | |
| SCHEMBL1405569 | 0.78 | ESR2 (0.50) | SLC18A3HTR2C | |
| SCHEMBL4676148 | 0.76 | SLC18A3 (0.67) | SLC18A3SIGMAR1HTR2CQDPRHTR3A | |
| SCHEMBL7966782 | 0.76 | HTR2C (0.64) | SLC18A3SIGMAR1HTR2CQDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4312572-A | — | — | None | — | — | JP | disclosed |
| JP-H04312572-A | CYCLIC AMINE COMPOUND | TAKEDA CHEM IND LTD | 1992-11-04 | — | — | JP | disclosed |