Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 3/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12430464 | 0.84 | TSHR (0.57) | TSHRALDH1A1KMOHSD11B1POLB | |
| SCHEMBL21055987 | 0.82 | GSK3B (0.55) | TSHRALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL9533712 | 0.82 | TSHR (0.45) | TSHRALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL3502522 | 0.81 | KCNQ3 (0.46) | TSHRACHEKMOHSD11B1 | |
| SCHEMBL2075296 | 0.79 | CYP1A2 (0.51) | TSHRALDH1A1CYP3A4ACHEKMO | |
| SCHEMBL11637468 | 0.78 | USP5 (0.50) | TSHRALDH1A1HSD17B10KMT2A | |
| SCHEMBL11588759 | 0.78 | ALDH1A1 (0.41) | TSHRALDH1A1ACHEPLAAHSP90AB1 | |
| SCHEMBL11589494 | 0.76 | ALDH1A1 (0.52) | TSHRALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL1121596 | 0.75 | TSHR (0.68) | TSHRALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL3566736 | 0.75 | TSHR (0.50) | TSHRALDH1A1CYP3A4HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4356438-A | — | — | None | — | — | JP | disclosed |
| JP-H04356438-A | METHOD FOR PRODUCING ACETOPHENONE COMPOUNDS AND INTERMEDIATE THEREFOR AND METHOD FOR PRODUCING THE SAME | NIPPON NOHYAKU CO LTD | 1992-12-10 | — | — | JP | disclosed |