SCHEMBL9618656

SCHEMBL9618656

CC(=O)c1ccc2ccccc2c1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
CYP2A6 P11509 2/20 0.52
CYP1A2 P05177 1/20 0.52
HPGD P15428 3/20 0.50
MAPT P10636 2/20 0.50
ALDH1A1 P00352 2/20 0.50
WDR5 P61964 1/20 0.50
MAOB P27338 1/20 0.49
LDHA P00338 1/20 0.48
NCEH1 Q6PIU2 1/20 0.47
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
KDM4E B2RXH2 2/20 0.44
RAB9A P51151 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
NPC1 O15118 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM2B Q8NHM5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL295041 0.86 TSHR (0.54) TSHRCYP2A6CYP1A2HPGDMAPT
SCHEMBL11266839 0.84 TSHR (0.52) TSHRCYP2A6CYP1A2HPGDMAPT
SCHEMBL248146 0.84 WDR5 (0.66) TSHRCYP2A6CYP1A2HPGDALDH1A1
SCHEMBL6908614 0.82 WDR5 (0.63) TSHRCYP2A6CYP1A2HPGDALDH1A1
SCHEMBL6915351 0.82 WDR5 (0.63) TSHRCYP2A6CYP1A2HPGDALDH1A1
SCHEMBL6917503 0.82 WDR5 (0.63) TSHRCYP2A6CYP1A2HPGDALDH1A1
SCHEMBL6917500 0.82 WDR5 (0.63) TSHRCYP2A6CYP1A2HPGDALDH1A1
SCHEMBL6912830 0.82 WDR5 (0.63) TSHRCYP2A6CYP1A2HPGDALDH1A1
SCHEMBL1394794 0.82 ALDH1A1 (0.49) TSHRCYP2A6CYP1A2HPGDMAPT
SCHEMBL8679415 0.82 TSHR (0.50) TSHRCYP2A6CYP1A2HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109761775-B Method for purifying 4-acetyl-1-methylnaphthalene from acetyl methylnaphthalene mixture 湖北海力环保科技股份有限公司 2022-02-01 CN claimed
JP-4364152-A None JP disclosed
CN-109761775-B Method for purifying 4-acetyl-1-methylnaphthalene from acetyl methylnaphthalene mixture 湖北海力环保科技股份有限公司 2022-02-01 CN disclosed
CN-109761775-B Method for purifying 4-acetyl-1-methylnaphthalene from acetyl methylnaphthalene mixture 湖北海力环保科技股份有限公司 2022-02-01 CN disclosed
CN-109761775-B Method for purifying 4-acetyl-1-methylnaphthalene from acetyl methylnaphthalene mixture 湖北海力环保科技股份有限公司 2022-02-01 CN disclosed
US-20080132562-A1 TETRONIC AND TETRAMIC ACIDS GODEL THIERRY 2008-06-05 US disclosed
US-20080132562-A1 TETRONIC AND TETRAMIC ACIDS GODEL THIERRY 2008-06-05 US disclosed
US-20070197524-A1 Fluorenes and carbazoles as ligands of the EP2 receptor BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-08-23 US disclosed
US-20070197524-A1 Fluorenes and carbazoles as ligands of the EP2 receptor BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-08-23 US disclosed
WO-2007071456-A1 FLUORENES AND CARBAZOLES AS LIGANDS OF THE EP2 RECEPTOR BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-06-28 WO disclosed
JP-H04364152-A METHOD FOR RECOVERING CATALYST TEIJIN LTD 1992-12-16 JP disclosed
US-5138098-A Catalytic actlation using complexing agent AMOCO CORPORATION (US) 1992-08-11 US disclosed
US-5026917-A Acetylation of 2-methylnaphthalenes AMOCO CORPORATION (US) 1991-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132562-A1 TETRONIC AND TETRAMIC ACIDS BACE1, PSEN1, BACE2 TSHR 412/4885CYP2A6 1345/4885CYP1A2 2117/4885
US-20070197524-A1 Fluorenes and carbazoles as ligands of the EP2 receptor PTGER2, PTGER1, PTGDR2 TSHR 207/4885CYP2A6 434/4885CYP1A2 108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.