Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mandelic Acid SCHEMBL738154 | 0.79 | LMNA (0.51) | LMNAMAPK1SLC6A4SLC6A3SLC6A2 | |
| Mandelic Acid SCHEMBL738480 | 0.79 | LMNA (0.51) | LMNAMAPK1SLC6A4SLC6A3SLC6A2 | |
| Mandelic Acid SCHEMBL7703006 | 0.79 | LMNA (0.51) | LMNAMAPK1SLC6A4SLC6A3SLC6A2 | |
| Mandelic Acid SCHEMBL7700968 | 0.79 | LMNA (0.51) | LMNAMAPK1SLC6A4SLC6A3SLC6A2 | |
| Mandelic Acid SCHEMBL738482 | 0.79 | LMNA (0.51) | LMNAMAPK1SLC6A4SLC6A3SLC6A2 | |
| Mandelic Acid SCHEMBL16278854 | 0.79 | LMNA (0.55) | LMNAMAPK1SLC6A4SLC6A3SLC6A2 | |
| Cadaverine Tartrate SCHEMBL4338640 | 0.77 | TSHR (0.40) | LMNASLC6A4SLC6A3SLC6A2SMN1; SMN2 | |
| Cadaverine Tartrate SCHEMBL7749321 | 0.77 | TSHR (0.40) | LMNASLC6A4SLC6A3SLC6A2SMN1; SMN2 | |
| Cadaverine Tartrate SCHEMBL4322353 | 0.77 | TSHR (0.40) | LMNASLC6A4SLC6A3SLC6A2SMN1; SMN2 | |
| Cadaverine Tartrate SCHEMBL7743890 | 0.77 | TSHR (0.40) | LMNASLC6A4SLC6A3SLC6A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4360877-A | — | — | None | — | — | JP | disclosed |
| JP-H04360877-A | PRODUCTION OF OPTICALLY ACTIVE 2-METHYLPIPERAZINE MANDELATE AND OPTICALLY ACTIVE 2-METHYLPIPERAZINE | YAMAKAWA YAKUHIN KOGYO KK | 1992-12-14 | — | — | JP | disclosed |