Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mandelic Acid SCHEMBL738154 | 1.00 | LMNA (0.51) | LMNAMAPK1KMT2ASLC6A2SLC6A4 | |
| Mandelic Acid SCHEMBL738480 | 1.00 | LMNA (0.51) | LMNAMAPK1KMT2ASLC6A2SLC6A4 | |
| Mandelic Acid SCHEMBL738482 | 1.00 | LMNA (0.51) | LMNAMAPK1KMT2ASLC6A2SLC6A4 | |
| Mandelic Acid SCHEMBL7703006 | 1.00 | LMNA (0.51) | LMNAMAPK1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL1995231 | 0.86 | PTGS2 (0.45) | — | |
| Mandelic Acid SCHEMBL522946 | 0.83 | LMNA (0.64) | LMNAMAPK1SLC6A2SLC6A4SLC6A3 | |
| Mandelic Acid SCHEMBL9618665 | 0.79 | LMNA (0.55) | LMNAMAPK1KMT2ASLC6A2SLC6A4 | |
| Mandelic Acid SCHEMBL6950424 | 0.79 | KMT2A (0.49) | LMNAMAPK1KMT2A | |
| Mandelic Acid SCHEMBL27837822 | 0.78 | LMNA (0.67) | LMNAMAPK1KMT2ASLC6A2SLC6A4 | |
| Mandelic Acid SCHEMBL16278854 | 0.77 | LMNA (0.55) | LMNAMAPK1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101258138-A | Phenoxypropylpiperidines and -pyrrolidines and their use as histamine h3-receptor ligands | BIOPROJET SOC CIV (FR) | 2008-09-03 | — | — | CN | disclosed |
| US-6342511-B1 | RACEMIC, ENANTIOMORPHS AND DIASTERIOMORPHS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-01-29 | — | — | US | disclosed |
| EP-0986555-A1 | NOVEL PHENCYCLIDINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998055478-A1 | NOVEL PHENCYCLIDINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-12-10 | — | — | WO | disclosed |