SCHEMBL9619008

SCHEMBL9619008

CCCCCCCCc1ccc(Nc2ccccc2CC)c(CC)c1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 4/20 0.45
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
GPR3 P46089 1/20 0.43
PLK3 Q9H4B4 3/20 0.43
RORA P35398 1/20 0.43
RORC P51449 1/20 0.43
RORB Q92753 1/20 0.43
HTR2A P28223 1/20 0.42
KAT8 Q9H7Z6 2/20 0.41
POLB P06746 1/20 0.41
PPARA Q07869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10632221 1.00 PLK1 (0.45) PLK1KDM4EALDH1A1GAAMAPT
SCHEMBL4305481 0.92 KAT8 (0.46) KDM4EALDH1A1HTR2AKAT8PPARA
SCHEMBL1605185 0.92 KAT8 (0.46) KDM4EALDH1A1HTR2AKAT8PPARA
SCHEMBL29935883 0.92 KAT8 (0.46) KDM4EALDH1A1HTR2AKAT8PPARA
SCHEMBL9468687 0.82 ESR1 (0.44) KDM4EALDH1A1MAPTSMN1; SMN2GPR3
SCHEMBL14785526 0.79 LIPG (0.56) KAT8PPARA
SCHEMBL29785474 0.79 LIPG (0.56) KAT8PPARA
SCHEMBL1567827 0.79 LIPG (0.56) KAT8PPARA
SCHEMBL9418574 0.79 LIPG (0.56) KAT8PPARA
SCHEMBL10869653 0.79 LIPG (0.56) KAT8PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0136377-B2 OLIGOMERIZATION OF OLEFINS AND SYNTHETIC LUBRICANT COMPRISING OLEFIN OLIGOMERS TEXACO DEVELOPMENT CORPORATION (US) 1992-01-22 EP disclosed
US-4739121-A Process for otho- and para-alkylating diphenylamines THE B. F. GOODRICH COMPANY (US) 1988-04-19 US disclosed
EP-0136377-B1 OLIGOMERIZATION OF OLEFINS AND SYNTHETIC LUBRICANT COMPRISING OLEFIN OLIGOMERS TEXACO DEVELOPMENT CORPORATION (US) 1988-04-13 EP disclosed
EP-0136377-A1 Oligomerization of olefins and synthetic lubricant comprising olefin oligomers TEXACO DEVELOPMENT CORPORATION (US) 1985-04-10 EP disclosed
US-4420647-A OLIGOMERS OF 9-24 CARBON INTERNAL OLEFINS AND ALPHA OLEFINS USING BORON TRIFLUORIDE CATALYST TEXACO INC. (US) 1983-12-13 US disclosed
US-4354950-A ANTISLUDGE AGENTS FOR INTERNAL COMBUSTION ENGINES TEXACO INC. (US) 1982-10-19 US disclosed
US-4339336-A Quaternary ammonium succinimide salt composition and lubricating oil containing same TEXACO INC. (US) 1982-07-13 US disclosed
US-4338206-A Quaternary ammonium succinimide salt composition and lubricating oil containing same TEXACO INC. (US) 1982-07-06 US disclosed
US-4326973-A DISPERSANTS TEXACO INC. (US) 1982-04-27 US disclosed
US-4306070-A ACID CATALYZED LACTONIZATION TEXACO INC. (US) 1981-12-15 US disclosed
US-4273663-A Quaternary ammonium diester salt composition and lubricating oil containing same TEXACO INC. (US) 1981-06-16 US disclosed
US-4253980-A ANTISLUDGE AGENT TEXACO INC. (US) 1981-03-03 US disclosed
US-4251380-A DISPERSANT TEXACO INC. (US) 1981-02-17 US disclosed
US-4248719-A FROM ALKENYLSUCCINIMIDES OR SUCCINATES, SUBSTITUTED ARYL CARBOXY ACIDS TEXACO INC. (US) 1981-02-03 US disclosed
US-4194981-A DISPERSNATS, DETERGENTS TEXACO INC. (US) 1980-03-25 US disclosed
US-4000162-A DETERGENT, DISPERSANT FOR LUBRICATING OILS TEXACO INC. (US) 1976-12-28 US disclosed
US-3996240-A DETERGENT-DISPERSANT LUBRICANT ADDITIVE TEXACO INC. (US) 1976-12-07 US disclosed
US-3960889-A DETERGENT-DISPERSANT IN OIL AND HYDROCARBON LUBRICANT TEXACO INC. (US) 1976-06-01 US disclosed