SCHEMBL1605185

SCHEMBL1605185

CCCCCCCCCc1ccc(Nc2ccc(CCCCCCCCC)cc2CC)c(CC)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 2/20 0.46
PPARA Q07869 2/20 0.46
ESR1 P03372 2/20 0.46
ADRA2A P08913 2/20 0.46
ADORA3 P0DMS8 2/20 0.46
TACR2 P21452 2/20 0.46
SLC6A2 P23975 2/20 0.46
SLC6A4 P31645 2/20 0.46
SLC6A3 Q01959 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
SHBG P04278 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
HSPD1 P10809 1/20 0.46
ADRB3 P13945 1/20 0.46
HTR2C P28335 1/20 0.46
HSPE1 P61604 1/20 0.46
HIF1A Q16665 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29935883 1.00 KAT8 (0.46) KAT8PPARAESR1ADRA2AADORA3
SCHEMBL4305481 1.00 KAT8 (0.46) KAT8PPARAESR1ADRA2AADORA3
SCHEMBL10632221 0.92 PLK1 (0.45) KAT8PPARAKDM4EALDH1A1HTR2A
SCHEMBL9619008 0.92 PLK1 (0.45) KAT8PPARAKDM4EALDH1A1HTR2A
SCHEMBL9468687 0.89 ESR1 (0.44) KAT8PPARAESR1ADRA2AADORA3
SCHEMBL25127087 0.84 SKP2 (0.46) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL24037355 0.79 PPARA (0.58) KAT8PPARAESR1ADRA2AADORA3
SCHEMBL1604988 0.79 P2RX7 (0.43) KDM4EALDH1A1LMNA
SCHEMBL29625809 0.79 P2RX7 (0.43) KDM4EALDH1A1LMNA
SCHEMBL10415499 0.79 KAT8 (0.49) KAT8PPARAESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4263481-B1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER HUNTSMAN PETROCHEMICAL LLC (US) 2025-06-18 EP disclosed
US-12173247-B2 Reaction product of an organic amine and glycidol and its use as a friction modifier HUNTSMAN PETROCHEMICAL LLC 2024-12-24 US disclosed
US-20240018440-A1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER HUNTSMAN PETROCHEMICAL LLC 2024-01-18 US disclosed
EP-4263481-A1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER Huntsman Petrochemical LLC (US) 2023-10-25 EP disclosed
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
US-20230097718-A1 BIOBASED EXTREME PRESSURE ADDITIVE FOR LUBRICATING COMPOSITIONS AND ASSOCIATED METHODS INGEVITY SOUTH CAROLINA, LLC 2023-03-30 US disclosed
EP-2880140-B2 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINES SHELL INT RESEARCH (NL) 2023-03-08 EP disclosed
US-11512262-B2 Azaphenothiazines and azaphenoxazines as antioxidants UNIVERSITY OF OTTAWA (CA) 2022-11-29 US disclosed
CN-107001978-B Method for reducing low speed pre-ignition 国际壳牌研究有限公司 2022-07-19 CN disclosed
US-20220220408-A1 LUBRICANT THICKENER SYSTEMS FROM MODIFIED TALL OIL FATTY ACIDS, LUBRICATING COMPOSITIONS, AND ASSOCIATED METHODS MAINSTREAM PINE PRODUCTS, LLC 2022-07-14 US disclosed
US-20040053794-A1 Lubricating oil composition SHELL OIL COMPANY 2004-03-18 US disclosed
WO-2002079358-A2 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2002-10-10 WO disclosed
EP-1109882-B1 LUBRICATING OIL COMPOSITION USEFUL IN HYDRAULIC FLUIDS SHELL INT RESEARCH (NL) 2002-07-17 EP disclosed
EP-0674615-B1 DECOLORIZATION OF ALKYLATED DIARYLAMINES GOODRICH CO B F (US) 1997-06-04 EP disclosed
EP-0674615-A1 DECOLORIZATION OF ALKYLATED DIARYLAMINES. GOODRICH CO B F (US) 1995-10-04 EP disclosed
WO-1994014753-A1 DECOLORIZATION OF ALKYLATED DIARYLAMINES THE B.F. GOODRICH COMPANY (US) 1994-07-07 WO disclosed
US-5321159-A Decolorization of alkylated diarylamines THE B. F. GOODRICH COMPANY (US) 1994-06-14 US disclosed
US-4739121-A Process for otho- and para-alkylating diphenylamines THE B. F. GOODRICH COMPANY (US) 1988-04-19 US disclosed
EP-0260651-A2 Process for the preparation of a composition of parabutylated and octylated, ortho-ethylated diphenylamines The B.F. GOODRICH Company (US) 1988-03-23 EP disclosed
US-4704219-A Novel composition of para-butylated and octylated, ortho-ethylated diphenylamines THE B. F. GOODRICH COMPANY 1987-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11512262-B2 Azaphenothiazines and azaphenoxazines as antioxidants GPX4, LPO, GPX1 KAT8 1489/4885PPARA 411/4885ESR1 2270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.