⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10515737 | 0.81 | — | — | |
| SCHEMBL9618984 | 0.81 | — | — | |
| SCHEMBL8412576 | 0.77 | THRB (0.32) | — | |
| SCHEMBL9618872 | 0.77 | — | — | |
| SCHEMBL11970800 | 0.72 | — | — | |
| SCHEMBL4490226 | 0.70 | — | — | |
| SCHEMBL723921 | 0.63 | — | — | |
| SCHEMBL4849853 | 0.63 | — | — | |
| SCHEMBL6411494 | 0.63 | — | — | |
| SCHEMBL6411507 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169960-A | Process for the production of E/Z mixtures of 2-(bicyclo[3.3.0]octan-3-ylidene)-acetic acid derivatives with predominant E or Z portion | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-12-08 | — | — | US | disclosed |
| EP-0303562-B1 | Process for the preparation of E/Z mixtures of 2-(bicyclo[3.3.0]octan-3-ylidene) acetic-acid derivatives with a major proportion of E or Z isomer | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-01-15 | — | — | EP | disclosed |