Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619171 | 0.87 | SMN1; SMN2 (0.57) | GAAKDM4EALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10418857 | 0.86 | SMN1; SMN2 (0.56) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9619146 | 0.84 | KDM4E (0.55) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9619063 | 0.84 | KDM4E (0.52) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3365592 | 0.84 | CYP1A2 (0.56) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9619085 | 0.83 | ALDH1A1 (0.46) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8798665 | 0.82 | NPSR1 (0.46) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9619183 | 0.82 | KDM4E (0.50) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9619060 | 0.82 | KDM4E (0.50) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9619057 | 0.82 | KDM4E (0.50) | GAAKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356412-B1 | USE OF 2-AMINO-4-MORPHOLINO-6-PROPYL-1,3,5-TRIAZINES IN THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF COGNITIVE AND MENTAL DISORDERS | U C B, S.A. (BE) | 1992-05-13 | — | — | EP | claimed |
| EP-0356413-B1 | 2-AMINO-4-MORPHOLINO-6-PROPYL-1,3,5-TRIAZINES | U C B, S.A. (BE) | 1992-01-29 | — | — | EP | claimed |
| US-4956363-A | 2-amino-4-morpholino-6-propyl-1,3,5-triazine | U C B S.A. (BE) | 1990-09-11 | — | — | US | claimed |
| US-4956367-A | COGNITION ACTIVATORS, ALZHEIMER*S DISEASE | U C B S.A. (BE) | 1990-09-11 | — | — | US | claimed |
| EP-0356412-A1 | Use of 2-amino-4-morpholino-6-propyl-1,3,5-triazines in the preparation of a medicament for the treatment of cognitive and mental disorders | U C B, S.A. (BE) | 1990-02-28 | — | — | EP | claimed |
| EP-0356413-A1 | 2-Amino-4-morpholino-6-propyl-1,3,5-triazines | U C B, S.A. (BE) | 1990-02-28 | — | — | EP | claimed |
| EP-0356412-B1 | USE OF 2-AMINO-4-MORPHOLINO-6-PROPYL-1,3,5-TRIAZINES IN THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF COGNITIVE AND MENTAL DISORDERS | U C B, S.A. (BE) | 1992-05-13 | — | — | EP | disclosed |
| EP-0356413-B1 | 2-AMINO-4-MORPHOLINO-6-PROPYL-1,3,5-TRIAZINES | U C B, S.A. (BE) | 1992-01-29 | — | — | EP | disclosed |
| US-4956363-A | 2-amino-4-morpholino-6-propyl-1,3,5-triazine | U C B S.A. (BE) | 1990-09-11 | — | — | US | disclosed |
| US-4956367-A | COGNITION ACTIVATORS, ALZHEIMER*S DISEASE | U C B S.A. (BE) | 1990-09-11 | — | — | US | disclosed |
| EP-0356412-A1 | Use of 2-amino-4-morpholino-6-propyl-1,3,5-triazines in the preparation of a medicament for the treatment of cognitive and mental disorders | U C B, S.A. (BE) | 1990-02-28 | — | — | EP | disclosed |
| EP-0356413-A1 | 2-Amino-4-morpholino-6-propyl-1,3,5-triazines | U C B, S.A. (BE) | 1990-02-28 | — | — | EP | disclosed |