Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619171 | 0.83 | SMN1; SMN2 (0.57) | LMNAMEN1ALDH1A1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL10418857 | 0.82 | SMN1; SMN2 (0.56) | LMNAMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL9619145 | 0.82 | GAA (0.50) | LMNAMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL9619085 | 0.80 | ALDH1A1 (0.46) | LMNAMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL9619146 | 0.78 | KDM4E (0.55) | LMNAMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL3365592 | 0.78 | CYP1A2 (0.56) | LMNAMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL9619063 | 0.78 | KDM4E (0.52) | MEN1ALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL11520095 | 0.77 | LMNA (0.51) | NPSR1LMNAHPGDGAAPIK3CA | |
| SCHEMBL9619183 | 0.76 | KDM4E (0.50) | LMNAMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL9619057 | 0.76 | KDM4E (0.50) | LMNAMEN1ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527117-B1 | Substituted cyclopropylamino-1,3,5-triazines | UCB SA (BE) | 1997-10-29 | — | — | EP | claimed |
| US-5348956-A | Antiinflammatory and antiasthmatic agents | UCB S.A. (BE) | 1994-09-20 | — | — | US | claimed |
| US-5258513-A | FOR TREATMENT OF ALZHEIMER'S DISEASE, SENILE DEMENTIA, EVOLUTIVE COGNITIVE PATHOLOGIES, DEPRESSION, ANXIETY, MOOD DISTURBANCES, INFLAMMATION AND ASTHMA | UCB S.A. (BE) | 1993-11-02 | — | — | US | claimed |
| EP-0527117-A1 | Substituted cyclopropylamino-1,3,5-triazines | U C B, S.A. (BE) | 1993-02-10 | — | — | EP | claimed |
| JP-6220026-A | — | — | None | — | — | JP | disclosed |
| EP-0527117-B1 | Substituted cyclopropylamino-1,3,5-triazines | UCB SA (BE) | 1997-10-29 | — | — | EP | disclosed |
| US-5348956-A | Antiinflammatory and antiasthmatic agents | UCB S.A. (BE) | 1994-09-20 | — | — | US | disclosed |
| JP-H06220026-A | SUBSTITUTED CYCLOPROPYLAMINO-1,3,5-TRIAZINE COMPOUND | UCB SA | 1994-08-09 | — | — | JP | disclosed |
| US-5258513-A | FOR TREATMENT OF ALZHEIMER'S DISEASE, SENILE DEMENTIA, EVOLUTIVE COGNITIVE PATHOLOGIES, DEPRESSION, ANXIETY, MOOD DISTURBANCES, INFLAMMATION AND ASTHMA | UCB S.A. (BE) | 1993-11-02 | — | — | US | disclosed |
| EP-0527117-A1 | Substituted cyclopropylamino-1,3,5-triazines | U C B, S.A. (BE) | 1993-02-10 | — | — | EP | disclosed |