Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FGR | P09769 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.46 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11180975 | 0.86 | FTO (0.59) | CYP1A1CYP1A2ADORA2AFTOMAPT | |
| SCHEMBL582033 | 0.84 | CYP1A1 (0.72) | CYP1A1CYP1A2ADORA2AFTOMAPT | |
| 1-Amino-2,4-Dibromoanthra-Quinone SCHEMBL3272427 | 0.84 | FTO (0.64) | CYP1A1CYP1A2ADORA2AFTOMAPT | |
| SCHEMBL10808664 | 0.82 | MEN1 (0.62) | CYP1A1CYP1A2ADORA2AFTOMAPT | |
| SCHEMBL27749669 | 0.82 | CYP1A1 (0.70) | CYP1A1CYP1A2ADORA2AFTOMAPT | |
| SCHEMBL29780301 | 0.79 | MEN1 (0.56) | CYP1A1CYP1A2ADORA2AFTOMAPT | |
| SCHEMBL2711627 | 0.79 | MEN1 (0.56) | CYP1A1CYP1A2ADORA2AFTOMAPT | |
| SCHEMBL11856284 | 0.79 | MEN1 (0.51) | CYP1A1CYP1A2ADORA2AMAPTMEN1 | |
| SCHEMBL3581453 | 0.79 | CYP1A1 (1.00) | CYP1A1CYP1A2ADORA2AMAPTMEN1 | |
| SCHEMBL31083050 | 0.79 | FTO (0.55) | CYP1A1CYP1A2ADORA2AFTOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250362-B1 | PROCESS FOR THE PREPARATION OF A MIXTURE OF 1-AMINO-2-CHLORO-4-HYDROXY-ANTHRAQUINONE AND 1-AMINO-2-BROMO-4-HYDROXY-ANTHRAQUINONE | CIBA-GEIGY AG (CH) | 1992-01-02 | — | — | EP | disclosed |
| US-4767573-A | Process for the preparation of a mixture of 1-amino-2-chloro-4-hydroxyanthraquinone and 1-amino-2-bromo-4-hydroxyanthraquinone | CIBA-GEIGY CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0250362-A1 | Process for the preparation of a mixture of 1-amino-2-chloro-4-hydroxy-anthraquinone and 1-amino-2-bromo-4-hydroxy-anthraquinone | CIBA-GEIGY AG (CH) | 1987-12-23 | — | — | EP | disclosed |