Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960791 | 0.87 | CTSD (0.46) | CTSDKDM4EKDM5CPHF8KDM2A | |
| SCHEMBL21661487 | 0.79 | HDAC1 (0.48) | KDM4EKDM5CPHF8KDM2AALDH1A1 | |
| SCHEMBL3537671 | 0.79 | LMNA (0.44) | ALDH1A1POLBARG1ARG2MEN1 | |
| SCHEMBL12138292 | 0.79 | MEN1 (0.52) | KDM4EMAPTALDH1A1L3MBTL1MEN1 | |
| SCHEMBL21661488 | 0.78 | CA12 (0.33) | ALDH1A1ARG1ARG2MEN1FAAH | |
| SCHEMBL3321078 | 0.76 | — | — | |
| SCHEMBL13160473 | 0.74 | CTSD (0.52) | CTSDKDM4EKDM5CPHF8KDM2A | |
| SCHEMBL960835 | 0.73 | — | — | |
| SCHEMBL13282148 | 0.73 | — | — | |
| SCHEMBL2179403 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248833-B1 | MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE | BRIDGESTONE CORP (JP) | 2014-03-26 | — | — | EP | disclosed |
| CN-102099380-B | Modified diene rubber, method for producing same, rubber composition using same, and tire | BRIDGESTONE CORP | 2014-03-12 | — | — | CN | disclosed |
| US-20130289165-A1 | COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2013-10-31 | — | — | US | disclosed |
| EP-2655495-A1 | COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE | Compagnie Générale des Etablissements Michelin (FR) | 2013-10-30 | — | — | EP | disclosed |
| US-8389641-B2 | Modified diene rubber, production method thereof, and rubber composition and tire using the rubber | BRIDGESTONE CORPORATION (JP) | 2013-03-05 | — | — | US | disclosed |
| WO-2012084821-A1 | COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2012-06-28 | — | — | WO | disclosed |
| CN-102099380-A | Modified diene rubber, method for producing the same, rubber composition using the same, and tire | BRIDGESTONE CORP | 2011-06-15 | — | — | CN | disclosed |
| US-20110003911-A1 | MODIFIED DIENE RUBBER, PRODUCTION METHOD THEREOF, AND RUBBER COMPOSITION AND TIRE USING THE RUBBER | BRIDGESTONE CORPORATION (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2248833-A1 | MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE | Bridgestone Corporation (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-20100249336-A1 | MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING SAME, AND RUBBER COMPOSITION AND TIRE USING SUCH A MODIFIED NATURAL RUBBER | BRIDGESTONE CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| CN-101842393-A | Modified natural rubber, process for producing the same, rubber composition and tire using the same | BRIDGESTONE CORP | 2010-09-22 | — | — | CN | disclosed |
| EP-2206730-A1 | MODIFIED NATURAL RUBBER, PROCESS FOR PRODUCTION OF THE SAME, AND RUBBER COMPOSITION AND TIRE EACH COMPRISING THE SAME | Bridgestone Corporation (JP) | 2010-07-14 | — | — | EP | disclosed |