Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.68 |
| ▸ | EGFR | P00533 | 8/20 | 0.64 |
| ▸ | CRHBP | P24387 | 1/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
| ▸ | JUN | P05412 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19050169 | 1.00 | NFE2L2 (1.00) | NFE2L2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL19050166 | 0.85 | NFE2L2 (0.74) | NFE2L2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL19050162 | 0.84 | NFE2L2 (0.72) | NFE2L2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL9619490 | 0.83 | NFE2L2 (0.71) | NFE2L2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL5691865 | 0.81 | NFE2L2 (0.67) | NFE2L2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL21030102 | 0.81 | KMT2A (1.00) | NFE2L2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL16745390 | 0.80 | NFE2L2 (0.66) | NFE2L2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL28005275 | 0.80 | NFE2L2 (0.65) | NFE2L2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL16745481 | 0.80 | EGFR (0.77) | NFE2L2KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL17077339 | 0.78 | EGFR (1.00) | NFE2L2EGFRXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4358133-A | — | — | None | — | — | JP | disclosed |
| JP-H04358133-A | NONLINEAR OPTICAL MATERIAL | HITACHI CHEM CO LTD | 1992-12-11 | — | — | JP | disclosed |