SCHEMBL9619490

SCHEMBL9619490

COc1ccc(OC)c(C=C2CCc3cc(OC)ccc3C2=O)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.71
CYP26A1 O43174 4/20 0.69
SMN1; SMN2 Q16637 4/20 0.69
ALDH1A1 P00352 4/20 0.69
MAPT P10636 3/20 0.69
MAPK1 P28482 1/20 0.69
CYP27A1 Q02318 2/20 0.67
CYP24A1 Q07973 4/20 0.66
MIF P14174 5/20 0.66
NPC1 O15118 4/20 0.65
RAB9A P51151 4/20 0.65
MEN1 O00255 4/20 0.65
KMT2A Q03164 4/20 0.65
HPGD P15428 2/20 0.65
LMNA P02545 2/20 0.65
KDM4E B2RXH2 2/20 0.64
NFKB1 P19838 1/20 0.64
NFKB2 Q00653 1/20 0.64
RELA Q04206 1/20 0.64
CYP19A1 P11511 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5691865 0.92 NFE2L2 (0.67) NFE2L2CYP26A1SMN1; SMN2ALDH1A1MAPT
SCHEMBL9619624 0.89 ALDH1A1 (0.79) CYP26A1SMN1; SMN2ALDH1A1MAPTMAPK1
SCHEMBL28833618 0.84 BCHE (0.74) CYP26A1SMN1; SMN2ALDH1A1MAPTMAPK1
SCHEMBL8938872 0.84 MIF (0.80) CYP26A1SMN1; SMN2ALDH1A1MAPTMAPK1
SCHEMBL19050169 0.83 NFE2L2 (1.00) NFE2L2ALDH1A1MAPTMEN1KMT2A
SCHEMBL9619456 0.83 NFE2L2 (1.00) NFE2L2ALDH1A1MAPTMEN1KMT2A
SCHEMBL28096059 0.83 CYP26A1 (0.67) CYP26A1SMN1; SMN2ALDH1A1MAPTMAPK1
SCHEMBL28096102 0.82 BCHE (0.74) CYP26A1SMN1; SMN2ALDH1A1MAPTMAPK1
SCHEMBL6958968 0.82 MIF (0.85) CYP26A1SMN1; SMN2ALDH1A1MAPTMAPK1
SCHEMBL5692075 0.82 ALDH1A1 (0.75) NFE2L2CYP26A1SMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4358132-A None JP disclosed
JP-H04358132-A NONLINEAR OPTICAL MATERIAL HITACHI CHEM CO LTD 1992-12-11 JP disclosed