Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TYR | P14679 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11591708 | 0.93 | ESR1 (0.57) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL9065620 | 0.93 | ESR1 (0.57) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL17841 | 0.93 | ESR1 (0.65) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL218636 | 0.93 | ESR1 (0.65) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL11591869 | 0.93 | ESR1 (0.65) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL37079 | 0.93 | ESR1 (0.65) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL723515 | 0.93 | ESR1 (0.65) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL23484444 | 0.86 | MMP3 (0.64) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL28212104 | 0.86 | MMP3 (0.64) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| Phenol SCHEMBL28212107 | 0.85 | TDP1 (0.65) | ESR1ESR2CYP3A4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284955-B1 | STABILIZED BLENDS OF THERMOPLASTIC POLYESTER AND OF RUBBERY POLYMERIZATE, PROCESS FOR THE FABRICATION OF THESE BLENDS AND THEIR USE FOR THE FABRICATION OF MOULDED ARTICLES | BAYER AG (DE) | 1992-01-15 | — | — | EP | disclosed |