SCHEMBL218636

SCHEMBL218636

Oc1ccc(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.65
ESR2 Q92731 9/20 0.65
CYP3A4 P08684 3/20 0.65
ALDH1A1 P00352 2/20 0.65
LMNA P02545 2/20 0.55
TYR P14679 2/20 0.55
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA3 P07451 2/20 0.53
CA4 P22748 2/20 0.53
CA9 Q16790 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
CA14 Q9ULX7 2/20 0.53
GLA P06280 1/20 0.53
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
HPGD P15428 2/20 0.48
HSD17B10 Q99714 2/20 0.48
AR P10275 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11591869 1.00 ESR1 (0.65) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL17841 1.00 ESR1 (0.65) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL723515 1.00 ESR1 (0.65) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL37079 1.00 ESR1 (0.65) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL23484444 0.93 MMP3 (0.64) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL9619475 0.93 ESR1 (0.58) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL9065620 0.91 ESR1 (0.57) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL20520408 0.91 LMNA (0.73) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL11591708 0.91 ESR1 (0.57) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL11481828 0.89 ESR1 (0.59) ESR1ESR2CYP3A4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 989 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116333458-B High-temperature-resistant biodegradable agricultural film for rice based on graphene and multiwall carbon nanotube composite material 大禾科技发展(南京)有限公司 2023-12-01 CN claimed
CN-116333458-A High-temperature-resistant biodegradable agricultural film for rice based on graphene and multiwall carbon nanotube composite material 大禾科技发展(南京)有限公司 2023-06-27 CN claimed
CN-113999351-A Self-thickening acrylic emulsion with excellent water whitening resistance of core-shell structure and preparation method thereof 佛山市顺德区巴德富实业有限公司 2022-02-01 CN claimed
EP-3219708-B1 PROCESS FOR PRODUCING POLYVALENT GLYCIDYL COMPOUND SHOWA DENKO KK (JP) 2019-10-23 EP claimed
CN-107082877-B A method of preparing nontransparent type polysiloxane-polycarbonate random copolymer 广东新通彩材料科技有限公司 2019-05-03 CN claimed
US-20170342042-A1 PROCESS FOR PRODUCING POLYVALENT GLYCIDYL COMPOUND SHOWA DENKO K.K. (JP) 2017-11-30 US claimed
EP-3219708-A1 PROCESS FOR PRODUCING POLYVALENT GLYCIDYL COMPOUND Showa Denko K.K. (JP) 2017-09-20 EP claimed
CN-107082877-A A kind of method for preparing nontransparent type polysiloxane polycarbonate random copolymer 中山市通彩化工科技有限公司 2017-08-22 CN claimed
CN-104271640-B Prepare method and the polysulfones of polysulfones 埃姆斯专利股份公司 2016-12-21 CN claimed
US-20150126635-A1 METHOD FOR THE PRODUCTION OF POLYSULFONES, AND POLYSULFONES EMS-PATENT AG (CH) 2015-05-07 US claimed
EP-0668015-B1 Pesticidal compositions containing zinc oxide GB BIOSCIENCES CORP (US) 2000-05-24 EP claimed
EP-0067850-B1 BLENDS OF COPOLY (ESTER-CARBONATE) WITH POLYSULFONE GENERAL ELECTRIC COMPANY (US) 1985-11-13 EP claimed
EP-0067850-A4 BLENDS OF COPOLY (ESTER-CARBONATE) WITH POLYSULFONE. GEN ELECTRIC (US) 1983-04-18 EP claimed
EP-0067850-A1 BLENDS OF COPOLY (ESTER-CARBONATE) WITH POLYSULFONE. GEN ELECTRIC (US) 1982-12-29 EP claimed
US-4358569-A FLAME RESISTANT THERMOPLASTIC MOLDING MATERIAL OF GOOD IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1982-11-09 US claimed
WO-1982002401-A1 BLENDS OF COPOLYESTER-CARBONATE WITH POLYSULFONE GEN ELECTRIC (US) 1982-07-22 WO claimed
US-3988355-A PROSTAGLANDIN E1; HYPOTENSIVE AGENTS, OXYTOCICS, ANTISECRETORY AGENTS THE UPJOHN COMPANY (US) 1976-10-26 US claimed
US-3987067-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-10-19 US claimed
US-3969464-A PROSTAGLANDIN THE UPJOHN COMPANY (US) 1976-07-13 US claimed
US-3962289-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-06-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170342042-A1 PROCESS FOR PRODUCING POLYVALENT GLYCIDYL COMPOUND HAO2, NOX4, PPOX ESR1 3646/4885ESR2 3531/4885CYP3A4 1426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.