Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352558 | 0.88 | CA12 (0.61) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL29705954 | 0.88 | CA12 (0.61) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL5027571 | 0.85 | LMNA (0.70) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL9760958 | 0.85 | LMNA (0.70) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL3974361 | 0.83 | CA12 (0.65) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL30595409 | 0.83 | CA12 (0.65) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL9702108 | 0.82 | HSD17B10 (0.62) | LMNAMAPTKDM4EKMT2ACA12 | |
| SCHEMBL11049580 | 0.81 | LMNA (0.61) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL4787074 | 0.81 | HPGD (0.73) | LMNAMAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL12925820 | 0.81 | GLA (0.61) | LMNAMAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467826-A2 | Linear polymers | CIBA-GEIGY AG (CH) | 1992-01-22 | — | — | EP | disclosed |