Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5040450 | 0.92 | CYP3A4 (0.61) | LMNACYP3A4ACHEMTNR1BMTNR1A | |
| SCHEMBL11840503 | 0.90 | LMNA (0.54) | LMNACYP3A4ACHEMTNR1BMTNR1A | |
| SCHEMBL2707543 | 0.88 | SRD5A2 (0.62) | LMNACYP3A4ELANEKDM4EGAA | |
| SCHEMBL17028900 | 0.88 | LMNA (0.76) | LMNACYP3A4ACHEELANEMAPT | |
| SCHEMBL249305 | 0.88 | LMNA (0.76) | LMNACYP3A4ACHEELANEMAPT | |
| SCHEMBL26009141 | 0.87 | MTNR1B (0.59) | LMNACYP3A4ACHEMTNR1BMTNR1A | |
| SCHEMBL8390971 | 0.86 | AKR1C3 (0.53) | MTNR1BMTNR1AMAPTMEN1KMT2A | |
| SCHEMBL1821477 | 0.86 | ELANE (0.68) | LMNACYP3A4ELANEMAPTMEN1 | |
| SCHEMBL9760958 | 0.85 | LMNA (0.70) | LMNACYP3A4ACHEELANEMAPT | |
| SCHEMBL5027571 | 0.85 | LMNA (0.70) | LMNACYP3A4ACHEELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026991-B1 | AROMATIC POLYESTER AND FILAMENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4269965-A | COMPRISING MONOMERS OF P-HYDROXYBENZOIC ACID, 3,4'-DIHYDROXYBENZOPHENONE OR TEREPHTHALOYLDI(3-METHYL-4-HYDROXYBENZENE, AND TEREPHTHALIC ACID; LUSTER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-26 | — | — | US | disclosed |
| EP-0026991-A1 | Aromatic polyester and filaments | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-04-15 | — | — | EP | disclosed |