Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619759 | 0.86 | PPARG (0.35) | PPARGPPARAIDO1OPRM1KCNJ5 | |
| SCHEMBL9619728 | 0.78 | TSHR (0.41) | IDO1TAAR1ALDH1A1MAPTSCN2A | |
| SCHEMBL9619820 | 0.76 | TAAR1 (0.42) | PPARGPPARAOPRM1TAAR1ALDH1A1 | |
| SCHEMBL9619923 | 0.73 | TAAR1 (0.50) | TAAR1ALDH1A1MAPTKMT2A | |
| SCHEMBL9619732 | 0.72 | TAAR1 (0.42) | TAAR1LMNAALDH1A1MEN1KMT2A | |
| Bromide SCHEMBL10624508 | 0.71 | PPARG (0.38) | PPARGPPARAIDO1OPRM1KCNJ5 | |
| SCHEMBL9619683 | 0.68 | TAAR1 (0.38) | IDO1TAAR1ALDH1A1 | |
| SCHEMBL9619774 | 0.67 | IDO1 (0.43) | IDO1PYCR1MEN1KMT2ARAPGEF4 | |
| SCHEMBL18768745 | 0.66 | IDO1 (0.44) | IDO1KCNJ5KCNJ3LMNAPYCR1 | |
| SCHEMBL27543612 | 0.66 | GRM1 (0.43) | PPARGPPARAPYCR1MAPTRAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214842-B1 | ORGANOTIN COMPOUNDS AND PESTICIDES CONTAINING THEM | SHIONOGI & CO., LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-4935408-A | Organotin compounds and pesticides containing them | SHIONOGI & CO., LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| US-4774235-A | MITICIDES | SHIONOGI & CO., LTD. (JP) | 1988-09-27 | — | — | US | disclosed |
| EP-0214842-A2 | Organotin compounds and pesticides containing them | SHIONOGI & CO., LTD. (JP) | 1987-03-18 | — | — | EP | disclosed |