Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.35 |
| ▸ | CACNG8 | Q8WXS5 | 4/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527924 | 0.78 | TDP1 (0.80) | TDP1GAAMAPTALDH1A1LMNA | |
| SCHEMBL9828402 | 0.74 | TDP1 (0.50) | TDP1GAAMAPTALDH1A1LMNA | |
| SCHEMBL9620111 | 0.73 | TDP1 (0.45) | TDP1GAAMAPTALDH1A1LMNA | |
| SCHEMBL5580256 | 0.72 | TDP1 (0.56) | TDP1GAAMAPTALDH1A1LMNA | |
| SCHEMBL9163270 | 0.72 | GAA (0.62) | TDP1GAAMAPTALDH1A1LMNA | |
| SCHEMBL2829814 | 0.71 | TDP1 (0.54) | TDP1GAAMAPTALDH1A1LMNA | |
| SCHEMBL7167731 | 0.71 | TDP1 (0.69) | TDP1GAAMAPTALDH1A1LMNA | |
| SCHEMBL8270572 | 0.69 | TDP1 (1.00) | TDP1GAAMAPTALDH1A1LMNA | |
| SCHEMBL9690927 | 0.69 | TDP1 (0.67) | TDP1GAAMAPTALDH1A1LMNA | |
| SCHEMBL1014744 | 0.69 | TDP1 (0.67) | TDP1GAAMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |