SCHEMBL9619976

SCHEMBL9619976

CCCCCOc1cc(N2C(=O)OC(C(C)C)C2=O)c(F)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPOX P50336 10/20 0.43
THRB P10828 3/20 0.35
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
TP53 P04637 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
THRA P10827 1/20 0.34
PDE4B Q07343 1/20 0.33
PDE4D Q08499 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9620198 0.94 PPOX (0.49) PPOX
SCHEMBL9619884 0.90 PPOX (0.47) PPOX
SCHEMBL9620031 0.84 PPOX (0.39) PPOX
SCHEMBL9620167 0.83 PPOX (0.45) PPOXTSHR
SCHEMBL9620064 0.83 PPOX (0.48) PPOXMEN1HPGDTSHRKMT2A
SCHEMBL9620114 0.81 PPOX (0.44) PPOXNPC1RAB9A
SCHEMBL9620055 0.79 PPOX (0.51) PPOX
SCHEMBL9619999 0.78 PPOX (0.47) PPOXMEN1HPGDTSHRKMT2A
SCHEMBL9620002 0.78 PPOX (0.45) PPOXMEN1KMT2A
SCHEMBL9619992 0.77 PPOX (0.36) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100457-A OXAZOLIDINEDIONE COMPOUNDS, THE PROCESS FOR PREPARING THE SAME AND HERBICIDAL COMPOSITION CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-03-31 US disclosed
EP-0382884-A1 Oxazolidinedione compounds, the process for preparing the same and herbicidal composition containing the same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1990-08-22 EP disclosed