SCHEMBL9620064

SCHEMBL9620064

CC(C)Oc1cc(N2C(=O)OC(C(C)C)C2=O)c(F)cc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPOX P50336 12/20 0.48
MEN1 O00255 1/20 0.38
NR1I2 O75469 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GAA P10253 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX12 P18054 1/20 0.36
CYP2C19 P33261 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9619999 0.90 PPOX (0.47) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL9619884 0.86 PPOX (0.47) PPOXCYP1A2CYP2C19KDM4E
SCHEMBL9620198 0.85 PPOX (0.49) PPOXPOLB
SCHEMBL9620114 0.85 PPOX (0.44) PPOXMAPT
SCHEMBL9620055 0.83 PPOX (0.51) PPOX
SCHEMBL9619976 0.83 PPOX (0.43) PPOXMEN1KMT2AHPGDTSHR
SCHEMBL9620002 0.82 PPOX (0.45) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL9620031 0.82 PPOX (0.39) PPOX
SCHEMBL9620167 0.82 PPOX (0.45) PPOXTDP1GAATSHR
SCHEMBL9619992 0.81 PPOX (0.36) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2085269-A None JP disclosed
JP-1316305-A None JP disclosed
US-5100457-A OXAZOLIDINEDIONE COMPOUNDS, THE PROCESS FOR PREPARING THE SAME AND HERBICIDAL COMPOSITION CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-03-31 US disclosed
EP-0382884-A1 Oxazolidinedione compounds, the process for preparing the same and herbicidal composition containing the same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1990-08-22 EP disclosed
JP-H0285269-A OXAZOLIDINE DERIVATIVE AND PRODUCTION THEREOF SAGAMI CHEM RES CENTER 1990-03-26 JP disclosed
JP-H01316305-A HERBICIDE CONTAINING OXAZOLIDINE DERIVATIVE AS ACTIVE COMPONENT SAGAMI CHEM RES CENTER 1989-12-21 JP disclosed