Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | HPGD | P15428 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620098 | 0.79 | TDP1 (0.47) | SMN1; SMN2KDM4EHPGDALDH1A1PARP1 | |
| SCHEMBL3608499 | 0.78 | PKM (0.49) | SMN1; SMN2NPSR1KDM4EHPGDMAPT | |
| SCHEMBL20644416 | 0.77 | NPSR1 (0.53) | SMN1; SMN2NPSR1KDM4EHPGDMAPT | |
| SCHEMBL2923502 | 0.76 | SMN1; SMN2 (0.78) | SMN1; SMN2NPSR1KDM4EHPGDMAPT | |
| SCHEMBL29488675 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2NPSR1KDM4EHPGDMAPT | |
| SCHEMBL28462815 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2NPSR1KDM4EHPGDMAPT | |
| SCHEMBL9619935 | 0.74 | KDM4E (0.43) | SMN1; SMN2NPSR1KDM4EHPGDMAPT | |
| SCHEMBL16598906 | 0.74 | SMN1; SMN2 (0.61) | SMN1; SMN2NPSR1KDM4EHPGDMAPT | |
| SCHEMBL10871977 | 0.72 | SMN1; SMN2 (0.52) | SMN1; SMN2NPSR1KDM4EHPGDMAPT | |
| SCHEMBL1131972 | 0.71 | MAPT (0.73) | SMN1; SMN2NPSR1KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |