Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619964 | 0.84 | PTPN1 (0.39) | PDE2AS1PR3PTPN1GABRB1GABRB2 | |
| SCHEMBL9620102 | 0.82 | ATM (0.46) | ACP1CTSSNPSR1AAK1 | |
| SCHEMBL4025172 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL30341846 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL10627562 | 0.77 | CTSS (0.43) | KDM4EALDH1A1S1PR3GABRB1GABRB2 | |
| SCHEMBL10875101 | 0.76 | CTSS (0.42) | KDM4EALDH1A1PDE2AS1PR3GABRB1 | |
| SCHEMBL10631836 | 0.75 | PTGS2 (0.47) | S1PR3GABRB1GABRB2CTSSCTSK | |
| SCHEMBL9619978 | 0.74 | SMN1; SMN2 (0.50) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL16333438 | 0.74 | PPARG (0.52) | PDE2AS1PR3GABRB1GABRB2CTSS | |
| SCHEMBL2833637 | 0.74 | PPARG (0.52) | PDE2AS1PR3GABRB1GABRB2CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |
| EP-0195947-A2 | Beta-lactam antibiotics, process for their preparation and their use as and in medicaments | BAYER AG (DE) | 1986-10-01 | — | — | EP | disclosed |