Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NSD1 | Q96L73 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1913640 | 0.70 | HSD17B10 (1.00) | HSD17B10MAPTRAB9ANSD1NSD2 | |
| SCHEMBL8977446 | 0.68 | ALDH1A1 (0.44) | HSD17B10MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL9620034 | 0.68 | TDP1 (0.44) | HSD17B10MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL14044812 | 0.68 | HSD17B10 (0.68) | HSD17B10MAPTRAB9ANSD1NSD2 | |
| SCHEMBL2271143 | 0.68 | HSD17B10 (0.68) | HSD17B10MAPTRAB9ANSD1NSD2 | |
| SCHEMBL21091214 | 0.67 | HSD17B10 (0.72) | HSD17B10MAPTRAB9ANSD1NSD2 | |
| SCHEMBL11698907 | 0.65 | HSD17B10 (0.64) | HSD17B10MAPTRAB9ANSD1NSD2 | |
| SCHEMBL10967379 | 0.65 | MAPT (0.63) | HSD17B10MAPTRAB9ANSD1ALDH1A1 | |
| SCHEMBL13846459 | 0.65 | HSD17B10 (0.68) | HSD17B10MAPTRAB9ANSD1NSD2 | |
| SCHEMBL22253414 | 0.65 | ALDH1A1 (0.68) | HSD17B10MAPTRAB9ANSD1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |