Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977446 | 0.89 | ALDH1A1 (0.44) | TDP1PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL9620111 | 0.74 | TDP1 (0.45) | TDP1GAAALDH1A1MAPTLMNA | |
| SCHEMBL10631932 | 0.72 | TDP1 (0.46) | TDP1GAAALDH1A1HTTMAPT | |
| SCHEMBL10631855 | 0.71 | TDP1 (0.49) | TDP1GAAALDH1A1HTTMAPT | |
| SCHEMBL92598 | 0.70 | HDAC4 (0.41) | PIK3CDPIK3CAPIK3CBPIK3CGGAA | |
| SCHEMBL13527924 | 0.70 | TDP1 (0.80) | TDP1GAAALDH1A1MAPTKDM4E | |
| SCHEMBL8252775 | 0.69 | TDP1 (0.67) | TDP1GAAALDH1A1MAPTKDM4E | |
| SCHEMBL9620041 | 0.68 | HSD17B10 (0.52) | TDP1ALDH1A1HTTMAPTLMNA | |
| SCHEMBL8251931 | 0.67 | CRBN (0.53) | TDP1GAAALDH1A1HTTMAPT | |
| SCHEMBL2829814 | 0.67 | TDP1 (0.54) | TDP1GAAALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |
| EP-0195947-A2 | Beta-lactam antibiotics, process for their preparation and their use as and in medicaments | BAYER AG (DE) | 1986-10-01 | — | — | EP | disclosed |