Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.60 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.49 |
| ▸ | RHOA | P61586 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620104 | 0.99 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1CYP1A2KDM4ENPC1 | |
| SCHEMBL9620100 | 0.99 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1CYP1A2KDM4ENPC1 | |
| SCHEMBL9620182 | 0.98 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1CYP1A2KDM4ENPC1 | |
| SCHEMBL9620343 | 0.88 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1KDM4ENPC1LMNA | |
| SCHEMBL4715212 | 0.81 | KMT2A (0.51) | CYSLTR2CYSLTR1CYP1A2KDM4ENPC1 | |
| SCHEMBL4715215 | 0.81 | KMT2A (0.51) | CYSLTR2CYSLTR1CYP1A2KDM4ENPC1 | |
| SCHEMBL4715210 | 0.81 | KMT2A (0.51) | CYSLTR2CYSLTR1CYP1A2KDM4ENPC1 | |
| SCHEMBL9620370 | 0.80 | RHOA (0.58) | CYSLTR2CYSLTR1KDM4ENPC1LMNA | |
| SCHEMBL9837331 | 0.78 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1KDM4ENPC1LMNA | |
| SCHEMBL9837337 | 0.78 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1KDM4ENPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228959-B1 | AMINOSTYRYL COMPOUND, LEUKOTRIENE ANTAGONISTIC COMPOSITION CONTAINING THE SAME AS EFFECTIVE INGREDIENTS AND METHOD OF ANTAGONIZING SRS BY EMPLOYING THE SAME | MITSUBISHI KASEI CORPORATION (JP) | 1992-03-18 | — | — | EP | disclosed |