Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620827 | 0.84 | KDM4E (0.61) | APPSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL9620598 | 0.83 | APP (0.71) | APPSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL316219 | 0.82 | SMN1; SMN2 (0.60) | APPSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL20131332 | 0.81 | RAB9A (0.51) | APPSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL29873401 | 0.81 | APP (0.68) | APPSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL483414 | 0.81 | APP (0.68) | APPSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL9620668 | 0.81 | APP (0.64) | APPSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL13806225 | 0.80 | APP (0.67) | APPKDM4ERAB9ANPC1SULT1A1 | |
| SCHEMBL315601 | 0.80 | PARP1 (0.58) | SMN1; SMN2KDM4ERAB9ANPC1PKM | |
| SCHEMBL316475 | 0.79 | KDM4E (0.56) | APPSMN1; SMN2KDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306708-B1 | NOVEL BENZOTHIAZOLE AND ANTIRHEUMATIC AGENT COMPRISING IT AS AN ACTIVE INGREDIENT | KANEBO, LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4910211-A | Containing a phenyl substituted in position 2 and an ester in position 4 | KANEBO LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0306708-A1 | Novel benzothiazole and antirheumatic agent comprising it as an active ingredient | KANEBO, LTD. (JP) | 1989-03-15 | — | — | EP | disclosed |