Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 6/20 | 0.32 |
| ▸ | ARG1 | P05089 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | ODC1 | P11926 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10618386 | 0.97 | FFAR1 (0.39) | FFAR1CPT2TDP1ACLYACACB | |
| SCHEMBL9620605 | 0.97 | FFAR1 (0.39) | FFAR1CPT2TDP1ACLYACACB | |
| SCHEMBL9620492 | 0.97 | FFAR1 (0.39) | FFAR1CPT2TDP1ACLYACACB | |
| SCHEMBL9620386 | 0.97 | FFAR1 (0.39) | FFAR1CPT2TDP1ACLYACACB | |
| SCHEMBL9620466 | 0.97 | FFAR1 (0.39) | FFAR1CPT2TDP1ACLYACACB | |
| SCHEMBL3666127 | 0.87 | LMNA (0.52) | FFAR1TDP1TSHRALDH1A1 | |
| SCHEMBL16860500 | 0.85 | CES2 (0.45) | FFAR1TDP1TSHRALDH1A1 | |
| SCHEMBL10736732 | 0.85 | CES2 (0.45) | FFAR1TDP1TSHRALDH1A1 | |
| SCHEMBL4812713 | 0.84 | LMNA (0.48) | FFAR1TDP1TSHRALDH1A1 | |
| SCHEMBL11755736 | 0.84 | AKR1B1 (0.39) | FFAR1TDP1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279978-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING ALPHA-HALOGENATED DICARBOXYLIC ACIDS | Epis S.A. (CH) | 1992-01-02 | — | — | EP | disclosed |
| US-4908385-A | Pharmaceuticals | EPIS S.A. (CH) | 1990-03-13 | — | — | US | disclosed |
| EP-0279978-A1 | Pharmaceutical compositions containing alpha-halogenated dicarboxylic acids | Epis S.A. (CH) | 1988-08-31 | — | — | EP | disclosed |
| WO-1988002746-A1 | MEDICAMENTS CONTAINING ALPHA-HALOGENATED DICARBOXYLIC ACIDS | EPIS S.A. (CH) | 1988-04-21 | — | — | WO | disclosed |