Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652892 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MMP8PDK1PDK2PDK3 | |
| SCHEMBL20569154 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MMP8LMNAHSD17B10ALOX15 | |
| SCHEMBL765474 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MMP8LMNAHSD17B10POLB | |
| SCHEMBL13070248 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MMP8LMNAHSD17B10ALOX15 | |
| SCHEMBL13537856 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MMP8LMNAHSD17B10ALOX15 | |
| SCHEMBL803891 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MMP8LMNAHSD17B10ALOX15 | |
| SCHEMBL803804 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MMP8LMNAHSD17B10ALOX15 | |
| SCHEMBL11825489 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MMP8LMNAHSD17B10ALOX15 | |
| SCHEMBL12868912 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MMP8LMNAHSD17B10POLB | |
| SCHEMBL2301890 | 0.72 | ALDH1A1 (0.39) | ALDH1A1MMP8PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278732-B1 | FLUORINE-CONTAINING VITAMIN D2 DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-5047564-A | Osteoporosis | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0278732-A1 | Fluorine-containing vitamin D2 derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1988-08-17 | — | — | EP | disclosed |