Sugi Predict

Sugi Predict / Compounds / SCHEMBL2301890

SCHEMBL2301890

SCHEMBL2301890

CCOC(=O)C(C(=O)OCC)C(C)(C)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.39
▸ HSD17B10 Q99714 2/20 0.38
▸ MAPT P10636 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ LMNA P02545 2/20 0.37
▸ ALOX15 P16050 1/20 0.36
▸ MGAM O43451 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ SI P14410 1/20 0.36
▸ MGAM2 Q2M2H8 1/20 0.36
▸ SOAT1 P35610 1/20 0.36
▸ MMP8 P22894 1/20 0.34
▸ PDK1 Q15118 1/20 0.34
▸ PDK2 Q15119 1/20 0.34
▸ PDK3 Q15120 1/20 0.34
▸ PDK4 Q16654 1/20 0.34
▸ CPB2 Q96IY4 1/20 0.33
▸ TRPA1 O75762 1/20 0.33
▸ TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20468921 0.92 HTT (0.41) ALDH1A1HSD17B10MAPTHTTSMN1; SMN2
SCHEMBL24832197 0.91 HSD17B10 (0.35) ALDH1A1HSD17B10MAPTHTTSMN1; SMN2
SCHEMBL20456817 0.90 HSD17B10 (0.39) ALDH1A1HSD17B10MAPTHTTSMN1; SMN2
SCHEMBL14999139 0.90 ALDH1A1 (0.38) ALDH1A1HSD17B10MAPTHTTSMN1; SMN2
SCHEMBL23005820 0.85 MAPT (0.34) ALDH1A1HSD17B10MAPTHTTSMN1; SMN2
SCHEMBL20739381 0.83 MAPT (0.34) HSD17B10MAPTHTTSMN1; SMN2
SCHEMBL20473345 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10MAPTHTTSMN1; SMN2
SCHEMBL334770 0.77 ALDH1A1 (0.46) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL18762464 0.74 ALDH1A1 (0.39) ALDH1A1HSD17B10MAPTHTTSMN1; SMN2
SCHEMBL3383070 0.74 ALDH1A1 (0.42) ALDH1A1HSD17B10MAPTHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1042372-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SPA (IT) 2004-07-14 — — EP claimed
CN-1146585-C catalyst component and catalyst for olefin polymerization ض� 2004-04-21 — — CN claimed
US-6605562-B1 Comprising TiCl4, MgCl2 and an electron donor compound selected from heteroatom containing esters of malonic acids; heteroatoms are preferably selected from F, Cl, Br, and Si BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-08-12 — — US claimed
CN-1292800-A catalyst component and catalyst for olefin polymerization MONTELL TECHNOLOGY COMPANY BV (NL) 2001-04-25 — — CN claimed
EP-4692076-A1 HIV INHIBITOR COMPOUNDS Gilead Sciences, Inc. (US) 2026-02-11 — — EP disclosed
EP-4665454-A1 IMIDAZOTRIAZINE IL-17A MODULATORS AND USES THEREOF Dice Alpha, Inc. (US) 2025-12-24 — — EP disclosed
US-12479853-B2 HIV inhibitor compounds GILEAD SCIENCES, INC. (US) 2025-11-25 — — US disclosed
EP-3909949-B1 ATAZANAVIR (ATV) ANALOGUES FOR TREATING HIV INFECTIONS GILEAD SCIENCES INC (US) 2025-10-15 — — EP disclosed
US-20250243187-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-07-31 — — US disclosed
US-20250042910-A1 HIV INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. 2025-02-06 — — US disclosed
US-12084455-B2 HIV inhibitor compounds GILEAD SCIENCES, INC. (US) 2024-09-10 — — US disclosed
WO-2024173173-A1 IMIDAZOTRIAZINE IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. (US) 2024-08-22 — — WO disclosed
US-6689850-B2 Process for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-02-10 — — US disclosed
US-20030207754-A1 Process for the polymerization of olefins MORINI GIAMPIERO (IT) 2003-11-06 — — US disclosed
US-20030207755-A1 Heteroatom containing malonates used in catalysts for the polymerization of olefins MORINI GIAMPIERO (IT) 2003-11-06 — — US disclosed
US-20030199388-A1 Catalysts for the polymerization of olefins EQUISTAR CHEMICALS, LP 2003-10-23 — — US disclosed
US-6605562-B1 Comprising TiCl4, MgCl2 and an electron donor compound selected from heteroatom containing esters of malonic acids; heteroatoms are preferably selected from F, Cl, Br, and Si BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-08-12 — — US disclosed
CN-1292800-A catalyst component and catalyst for olefin polymerization MONTELL TECHNOLOGY COMPANY BV (NL) 2001-04-25 — — CN disclosed
EP-1042372-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Montell Technology Company bv (NL) 2000-10-11 — — EP disclosed
WO-2000026259-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS MONTELL TECHNOLOGY COMPANY BV (NL) 2000-05-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243187-A1 ANTI-VIRAL COMPOUNDS EIF2AK2, ZC3HAV1, HAVCR2 ALDH1A1 2039/4885HSD17B10 1644/4885MAPT 1485/4885
US-12479853-B2 HIV inhibitor compounds NFATC1, SAMHD1, CCR5 ALDH1A1 1353/4885HSD17B10 1416/4885MAPT 1456/4885
US-12084455-B2 HIV inhibitor compounds NFATC1, SAMHD1, CCR5 ALDH1A1 1353/4885HSD17B10 1416/4885MAPT 1456/4885
US-20250042910-A1 HIV INHIBITOR COMPOUNDS NFATC1, SAMHD1, CCR5 ALDH1A1 1353/4885HSD17B10 1416/4885MAPT 1456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.