Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL121743 | 0.97 | PDPK1 (0.34) | PDPK1DHFRCA5ACA5BCYP1A2 | |
| Sulfuric Acid SCHEMBL4612293 | 0.97 | PDPK1 (0.34) | PDPK1DHFRCA5ACA5BCYP1A2 | |
| Sulfuric Acid SCHEMBL20815930 | 0.97 | PDPK1 (0.34) | PDPK1DHFRCA5ACA5BCYP1A2 | |
| Sulfuric Acid SCHEMBL10391851 | 0.86 | CYP1A2 (0.30) | DHFRCYP1A2 | |
| SCHEMBL20815929 | 0.83 | CCNA2 (0.31) | PDPK1 | |
| Sulfuric Acid SCHEMBL94088 | 0.83 | CYP1A2 (0.31) | PDPK1DHFRCYP1A2 | |
| Sulfuric Acid SCHEMBL28283741 | 0.83 | CYP1A2 (0.31) | PDPK1DHFRCYP1A2 | |
| Sulfuric Acid SCHEMBL4826011 | 0.83 | CYP1A2 (0.31) | PDPK1DHFRCYP1A2 | |
| Sulfuric Acid SCHEMBL11529048 | 0.83 | CA5A (0.40) | CA5ACA5BCYP1A2 | |
| Sulfuric Acid SCHEMBL11564899 | 0.83 | CA5A (0.40) | CA5ACA5BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154173-B1 | PTERIDINE DERIVATIVES, AN ANTICANCER COMPOSITION CONTAINING SAME AND A PROCESS FOR THE PRODUCTION OF SAID DERIVATIVES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-01-08 | — | — | EP | disclosed |
| EP-0424261-A1 | Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent | L'OREAL (FR) | 1991-04-24 | — | — | EP | disclosed |
| US-4820706-A | Pteridine derivatives and method of treating leukemia employing same | RESEARCH CORPORATION (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0154173-A2 | Pteridine derivatives, an anticancer composition containing same and a process for the production of said derivatives | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1985-09-11 | — | — | EP | disclosed |