Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546912 | 0.86 | BCHE (0.51) | SRD5A2IDO1KEAP1NFE2L2DAO | |
| SCHEMBL146509 | 0.84 | ESR1 (0.55) | ESR1PDCD1ESR2CD274ACHE | |
| SCHEMBL6546683 | 0.84 | ATM (0.48) | IDO1ESR1PDCD1ESR2CD274 | |
| SCHEMBL8382637 | 0.82 | ALOX5AP (0.51) | ESR1ALOX5AP | |
| Ammonia Solution, Strong SCHEMBL7995783 | 0.82 | ESR1 (0.52) | ESR1PDCD1ESR2CD274ACHE | |
| SCHEMBL1149394 | 0.82 | IDO1 (0.58) | SRD5A2IDO1ESR1ESR2DAO | |
| SCHEMBL11410252 | 0.82 | IDO1 (0.58) | SRD5A2IDO1ESR1ESR2DAO | |
| SCHEMBL6547480 | 0.80 | ACHE (0.43) | SRD5A2IDO1ESR1ESR2KEAP1 | |
| SCHEMBL6547850 | 0.80 | CYP1A2 (0.45) | IDO1ESR1PDCD1ESR2CD274 | |
| SCHEMBL8101702 | 0.79 | CYP3A4 (0.64) | IDO1ESR1PDCD1ESR2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316014-B1 | METHOD FOR PRODUCING ARYLETHYLENES | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1992-04-01 | — | — | EP | disclosed |
| US-4855519-A | Method for producing arylethylene | NIPPON PETROCHEMICALS COMPANY (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0316014-A2 | Method for producing arylethylenes | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1989-05-17 | — | — | EP | disclosed |