SCHEMBL146509

SCHEMBL146509

Cc1ccc(C(C)c2ccc(C)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.55
PDCD1 Q15116 1/20 0.55
ESR2 Q92731 1/20 0.55
CD274 Q9NZQ7 1/20 0.55
ACHE P22303 8/20 0.53
TDP1 Q9NUW8 1/20 0.53
CHRNA7 P36544 1/20 0.50
ALOX5 P09917 1/20 0.41
ALDH1A1 P00352 2/20 0.40
CA7 P43166 2/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
CYP19A1 P11511 1/20 0.38
HSD17B10 Q99714 1/20 0.38
STAT3 P40763 1/20 0.38
TSHR P16473 3/20 0.37
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL7995783 0.97 ESR1 (0.52) ESR1PDCD1ESR2CD274ACHE
SCHEMBL6548061 0.91 ESR1 (0.48) ESR1PDCD1ESR2CD274ACHE
SCHEMBL2846227 0.89 LMNA (0.50) ESR1PDCD1ESR2CD274ACHE
Ammonia Solution, Strong SCHEMBL10808062 0.87 LMNA (0.48) ESR1PDCD1ESR2CD274ACHE
SCHEMBL20132340 0.87 ACHE (0.65) ESR1PDCD1ESR2CD274ACHE
SCHEMBL14160194 0.87 ESR1 (0.44) ESR1PDCD1ESR2CD274ACHE
SCHEMBL2680435 0.87 ACHE (0.65) ESR1PDCD1ESR2CD274ACHE
SCHEMBL822908 0.87 ESR1 (0.80) ESR1PDCD1ESR2CD274ACHE
SCHEMBL22593785 0.87 ACHE (0.65) ESR1PDCD1ESR2CD274ACHE
SCHEMBL20132351 0.87 ACHE (0.65) ESR1PDCD1ESR2CD274ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120042093-A Environment-friendly thermosensitive paper with high scratch resistance and hardness and preparation method thereof 江苏理工学院 2025-05-27 CN claimed
CN-119711249-A Bisphenol-free thermosensitive coating composition and preparation method and application thereof 江苏理工学院 2025-03-28 CN claimed
US-4601920-A DISSOLVING METAL AROMATIC CARBOXYLATE IN ORGANIC SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 1986-07-22 US claimed
US-4228023-A Paraffinic insulating oils containing a diarylalkane GULF RESEARCH & DEVELOPMENT COMPANY (US) 1980-10-14 US claimed
US-4157353-A Process for recovering a dialkylarylketone GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-06-05 US claimed
US-4115464-A DEHYDROGENATION, METAL PHOSPHATE CATALYST THE STANDARD OIL COMPANY (US) 1978-09-19 US claimed
US-4093660-A SOLIDIFICATION GULF RESEARCH & DEVELOPMENT COMPANY (US) 1978-06-06 US claimed
US-4086277-A FROM 1,1-DI(P-TOLYL)ETHANE OR 1,1-BIS(3,4-DIMETHYLPHENYL)ETHANE BY HEATING IN NITRIC ACID AND WATER GULF RESEARCH & DEVELOPMENT COMPANY (US) 1978-04-25 US claimed
US-4022838-A 1,1-DIAR-KETONES, NITRIC ACID, WATER GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-05-10 US claimed
US-4018828-A SOLIDIFICATION GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-04-19 US claimed
JP-2101033-A None JP disclosed
JP-55045667-A None JP disclosed
JP-56030928-A None JP disclosed
JP-56030929-A None JP disclosed
JP-59155093-A None JP disclosed
US-4093660-A SOLIDIFICATION GULF RESEARCH & DEVELOPMENT COMPANY (US) 1978-06-06 US disclosed
US-4086277-A FROM 1,1-DI(P-TOLYL)ETHANE OR 1,1-BIS(3,4-DIMETHYLPHENYL)ETHANE BY HEATING IN NITRIC ACID AND WATER GULF RESEARCH & DEVELOPMENT COMPANY (US) 1978-04-25 US disclosed
US-4022838-A 1,1-DIAR-KETONES, NITRIC ACID, WATER GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-05-10 US disclosed
US-4018828-A SOLIDIFICATION GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-04-19 US disclosed
US-3978143-A PROCESS FOR PREPARING DIARYLDINITROETHYLENES GULF RESEARCH & DEVELOPMENT COMPANY (US) 1976-08-31 US disclosed