Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.36 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR7 | P34969 | 5/20 | 0.36 |
| ▸ | HTR6 | P50406 | 5/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | DNM2 | P50570 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1274458 | 1.00 | HTR1A (0.36) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL7598929 | 1.00 | HTR1A (0.36) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL2534130 | 0.98 | NPY1R (0.36) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL1274425 | 0.91 | HRH3 (0.37) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL25434244 | 0.87 | SLC29A1 (0.49) | TLR8SLC29A1DNM2 | |
| SCHEMBL11293174 | 0.87 | SLC29A1 (0.49) | TLR8SLC29A1DNM2 | |
| SCHEMBL21585426 | 0.82 | HSP90AA1 (0.36) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL4163258 | 0.82 | TLR8 (0.46) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL3809514 | 0.82 | HTR7 (0.47) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL4161007 | 0.82 | HTR7 (0.47) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240867-B1 | PROCESS FOR THE PREPARATION OF AMINOALKYL- OR -ARYLMELAMINES | BASF Aktiengesellschaft (DE) | 1992-02-19 | — | — | EP | disclosed |
| EP-0240867-A1 | Process for the preparation of aminoalkyl- or -arylmelamines | BASF Aktiengesellschaft (DE) | 1987-10-14 | — | — | EP | disclosed |