Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3896866 | 0.87 | MAPK1 (0.46) | MAPTL3MBTL1MAPK1NPSR1ALDH1A1 | |
| SCHEMBL4403990 | 0.85 | SLC6A4 (0.44) | MAPTL3MBTL1MAPK1NPSR1ALDH1A1 | |
| SCHEMBL9621843 | 0.81 | SLC6A4 (0.44) | MAPTL3MBTL1MAPK1NPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28178646 | 0.80 | SLC6A4 (0.43) | MAPTL3MBTL1MAPK1NPSR1ALDH1A1 | |
| SCHEMBL9621706 | 0.80 | SLC6A3 (0.46) | MAPTL3MBTL1MAPK1NPSR1ALDH1A1 | |
| SCHEMBL10704928 | 0.79 | SLC6A4 (0.43) | MAPTL3MBTL1MAPK1NPSR1ALDH1A1 | |
| SCHEMBL10566713 | 0.75 | SLC6A3 (0.48) | MAPTL3MBTL1MAPK1NPSR1ALDH1A1 | |
| SCHEMBL9622098 | 0.75 | NAAA (0.45) | MAPTL3MBTL1MAPK1NPSR1ALDH1A1 | |
| SCHEMBL28325086 | 0.74 | SLC6A3 (0.47) | MAPTL3MBTL1MAPK1NPSR1ALDH1A1 | |
| SCHEMBL25670058 | 0.74 | MAPT (0.53) | MAPTL3MBTL1MAPK1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269078-B1 | ISOMERIZATION PROCESS OF 2-CIS-PENTENOIC-ACID ESTERS TO 2-TRANS-PENTENOIC-ACID ESTERS | BASF Aktiengesellschaft (DE) | 1992-04-15 | — | — | EP | disclosed |
| EP-0269078-A2 | Isomerization process of 2-cis-pentenoic-acid esters to 2-trans-pentenoic-acid esters | BASF Aktiengesellschaft (DE) | 1988-06-01 | — | — | EP | disclosed |