Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651293 | 1.00 | ADORA2A (0.46) | ADORA2ACYP1A2ALDH1A1HTTTSHR | |
| SCHEMBL10646036 | 0.91 | CYP1A2 (0.54) | ADORA2ACYP1A2ALDH1A1HTTTSHR | |
| SCHEMBL9621914 | 0.91 | CYP1A2 (0.54) | ADORA2ACYP1A2ALDH1A1HTTTSHR | |
| SCHEMBL4099828 | 0.89 | ADORA2A (0.51) | ADORA2ACYP1A2ALDH1A1HTTLMNA | |
| SCHEMBL4099830 | 0.89 | ADORA2A (0.51) | ADORA2ACYP1A2ALDH1A1HTTLMNA | |
| SCHEMBL10866514 | 0.86 | ALDH1A1 (0.46) | ADORA2ACYP1A2ALDH1A1HTTTSHR | |
| SCHEMBL10866512 | 0.86 | ALDH1A1 (0.46) | ADORA2ACYP1A2ALDH1A1HTTTSHR | |
| SCHEMBL10415643 | 0.80 | MAPT (0.49) | ADORA2ACYP1A2ALDH1A1HTTTSHR | |
| SCHEMBL10616011 | 0.80 | CYP1A2 (0.57) | CYP1A2ALDH1A1HTTTSHRLMNA | |
| SCHEMBL10926832 | 0.79 | TAAR1 (0.44) | ADORA2ATSHRLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173322-B1 | 1-(2-OXYAMINOSULFONYLPHENYL-SULFONYL)-3-HETEROARYL UREAS | BAYER AG (DE) | 1988-12-28 | — | — | EP | claimed |
| EP-0470430-A1 | Process for the preparation of oxyguanidins | BAYER AG (DE) | 1992-02-12 | — | — | EP | disclosed |
| US-4797484-A | REACTING GUANIDINE DERIVATIVE WITH SULPHONYL HALIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |
| US-4645528-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-02-24 | — | — | US | disclosed |
| EP-0203220-A1 | Benzolactamsultams | BAYER AG (DE) | 1986-12-03 | — | — | EP | disclosed |
| US-4619688-A | Herbicidal sulfonylguanidine derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-28 | — | — | US | disclosed |
| EP-0148498-A1 | Sulfonylguanidine derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-07-17 | — | — | EP | disclosed |