Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456287 | 0.90 | CYP1A2 (0.59) | MAPTKMT2ACYP1A2ALDH1A1HTT | |
| SCHEMBL9456322 | 0.84 | RAB9A (0.58) | MAPTKMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL10616011 | 0.83 | CYP1A2 (0.57) | MAPTKMT2ACYP1A2ALDH1A1HTT | |
| SCHEMBL9621879 | 0.80 | ADORA2A (0.46) | MAPTKMT2ACYP1A2ALDH1A1HTT | |
| SCHEMBL10651293 | 0.80 | ADORA2A (0.46) | MAPTKMT2ACYP1A2ALDH1A1HTT | |
| SCHEMBL9129851 | 0.79 | CYP1A2 (0.61) | MAPTKMT2ACYP1A2ALDH1A1HTT | |
| SCHEMBL9739732 | 0.78 | CYP1A2 (0.50) | MAPTKMT2ACYP1A2ALDH1A1HTT | |
| SCHEMBL9368434 | 0.78 | CYP1A2 (0.59) | MAPTKMT2ACYP1A2ALDH1A1HTT | |
| SCHEMBL10503870 | 0.78 | CYP1A2 (0.46) | MAPTKMT2ACYP1A2ALDH1A1HTT | |
| SCHEMBL10416731 | 0.77 | MAPT (0.86) | MAPTKMT2AALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3623370-A1 | NOVEL TRF1 MODULATORS AND ANALOGUES THEREOF | Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) (ES) | 2020-03-18 | — | — | EP | disclosed |
| US-4904299-A | Herbicidal N-hydroxy-N'-sulfonylguanidines | E. I. DU PONT DE NEMOURS AND CO. (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0117014-B1 | HERBICIDAL N-HYDROXY-N'-SULFONYLGUANIDINES AND SULFONAMIDE INNER SALTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |
| US-4750930-A | Herbicidal N-hydroxy-N'-sulfonylguanidines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-14 | — | — | US | disclosed |
| US-4689070-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-08-25 | — | — | US | disclosed |
| EP-0117014-A1 | Herbicidal N-hydroxy-N'-sulfonylguanidines and sulfonamide inner salts | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-08-29 | — | — | EP | disclosed |