Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL27590479 | 0.91 | — | — | |
| Pyridine SCHEMBL9406460 | 0.91 | — | — | |
| Pyridine SCHEMBL28501576 | 0.91 | — | — | |
| Pyridine SCHEMBL29384311 | 0.86 | — | — | |
| Pyridine SCHEMBL16702934 | 0.86 | TP53 (0.30) | — | |
| Pyridine SCHEMBL30718930 | 0.86 | — | — | |
| Pyridine SCHEMBL30320033 | 0.86 | TP53 (0.30) | — | |
| Pyridine SCHEMBL31579081 | 0.86 | — | — | |
| Pyridine SCHEMBL1736019 | 0.86 | TP53 (0.30) | — | |
| Pyridine SCHEMBL31757303 | 0.86 | TP53 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106959-A | Intermediates for ceramics, gels, films, optical fibers, polymerization catalysts and silicone curing agents | RHONE-POULENC, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-5017695-A | With cerium ammonium nitrate and silanol-type compound | RHONE-POULENC, INC. (US) | 1991-05-21 | — | — | US | disclosed |
| US-5017694-A | With silanol-type compounds | RHONE-POULENC, INC. (US) | 1991-05-21 | — | — | US | disclosed |
| US-4920204-A | INTERMEDIATES FOR CERIC ALKOXIDES | RHONE-POULENC INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4703109-A | Tricyclopentadienyl cerium and process for preparing the same | RHONE-POULENC, INC. (US) | 1987-10-27 | — | — | US | disclosed |
| US-4663439-A | PAINT ADDITIVES, WATER REPELLENTS, ADHESION PROMOTORS MORDANTS, SIZING AGENTS, CATALYSTS AND CHEMICAL INTERMEDIATES | RHONE-POULENC, INC. (US) | 1987-05-05 | — | — | US | disclosed |
| US-4599201-A | OXIDATION OF CEROUS CARBVOXYLATE WITH AQUEOUS HYDROGEN PEROXIDE | RHONE-POULENC, INC. (US) | 1986-07-08 | — | — | US | disclosed |
| US-4492655-A | Tricyclopentadienyl cerium and process for preparing the same | RHONE-POULENC, INC. (US) | 1985-01-08 | — | — | US | disclosed |
| US-4489000-A | Process for the preparation of ceric alkoxides | RHONE-POULENC INC. (US) | 1984-12-18 | — | — | US | disclosed |