Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | PTGIR | P43119 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36116 | 0.91 | CLK4 (0.48) | MAPTMEN1KMT2AALDH1A1CLK4 | |
| SCHEMBL22129825 | 0.91 | CLK4 (0.48) | MAPTMEN1KMT2AALDH1A1CLK4 | |
| SCHEMBL10068859 | 0.89 | CLK4 (0.47) | MAPTMEN1KMT2AALDH1A1CLK4 | |
| Ethylene SCHEMBL22497430 | 0.87 | CLK4 (0.46) | MAPTMEN1KMT2AALDH1A1CLK4 | |
| SCHEMBL326391 | 0.87 | CLK4 (0.48) | MAPTMEN1KMT2AALDH1A1CLK4 | |
| SCHEMBL5692393 | 0.84 | SMN1; SMN2 (0.55) | MAPTMEN1KMT2ACLK4NPC1 | |
| SCHEMBL7114873 | 0.84 | S1PR1 (0.53) | MAPTMEN1KMT2AALDH1A1CLK4 | |
| SCHEMBL18344284 | 0.83 | KDM4E (0.44) | MAPTKMT2AALDH1A1CLK4NPC1 | |
| SCHEMBL3195574 | 0.82 | CYP1A2 (0.47) | MAPTALDH1A1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL274985 | 0.82 | APP (0.45) | MAPTALDH1A1CLK4NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271195-B1 | SUBSTITUTED TRIAZINE DERIVATIVES | Horsell Plc (GB) | 1992-04-22 | — | — | EP | claimed |
| EP-0319296-A2 | Photopolymerisable composition | Horsell Plc (GB) | 1989-06-07 | — | — | EP | claimed |
| EP-0271195-A1 | Substituted triazine derivatives | Horsell Plc (GB) | 1988-06-15 | — | — | EP | claimed |
| EP-0271195-B1 | SUBSTITUTED TRIAZINE DERIVATIVES | Horsell Plc (GB) | 1992-04-22 | — | — | EP | disclosed |
| US-4912218-A | Substituted triazine derivatives | COOKSON GROUP PLC (GB) | 1990-03-27 | — | — | US | disclosed |
| EP-0319296-A2 | Photopolymerisable composition | Horsell Plc (GB) | 1989-06-07 | — | — | EP | disclosed |
| EP-0271195-A1 | Substituted triazine derivatives | Horsell Plc (GB) | 1988-06-15 | — | — | EP | disclosed |