Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | RXRG | P48443 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17393750 | 0.95 | GABRA1 (0.46) | GABRA1GABRB2ACHERXRARXRB | |
| SCHEMBL2422576 | 0.91 | GABRA1 (0.44) | GABRA1GABRB2ACHERXRARXRB | |
| SCHEMBL2424035 | 0.91 | GABRA1 (0.44) | GABRA1GABRB2ACHERXRARXRB | |
| SCHEMBL12871778 | 0.89 | RXRA (0.45) | GABRA1GABRB2RXRARXRBRXRG | |
| SCHEMBL14228428 | 0.86 | HSPA5 (0.40) | GABRA1GABRB2ACHERXRARXRB | |
| SCHEMBL19051205 | 0.86 | TACR1 (0.43) | GABRA1GABRB2ACHERXRARXRB | |
| SCHEMBL12115600 | 0.86 | GABRA1 (0.62) | GABRA1GABRB2ACHERXRARXRB | |
| SCHEMBL12187819 | 0.84 | GABRA1 (0.38) | GABRA1GABRB2ACHERXRARXRB | |
| SCHEMBL19294284 | 0.84 | GABRA1 (0.38) | GABRA1GABRB2ACHERXRARXRB | |
| SCHEMBL12871594 | 0.84 | CYP4F2 (0.44) | GABRA1GABRB2ACHERXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330805-A | Preparation method of 3, 5-di-tert-butyl benzyl alcohol | 宁夏忠同生物科技有限公司 | 2025-01-21 | — | — | CN | claimed |
| EP-2961818-A1 | TRICRESYL PHOSPHATE-FREE OIL, LUBRICANT OR TURBINE OIL | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2016-01-06 | — | — | EP | claimed |
| WO-2014131571-A1 | TRICRESYL PHOSPHATE-FREE OIL, LUBRICANT OR TURBINE OIL | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2014-09-04 | — | — | WO | claimed |
| CN-101331138-A | One-pot synthesis of tetrazole derivatives of sirolimus | ABBOTT LAB (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1146905-A1 | COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | Algos Pharmaceutical Corporation (US) | 2001-10-24 | — | — | EP | claimed |
| WO-2000029022-A1 | COX-2 INHIBITORS IN COMBINATION WITH CENTRALLY ACTING ANALGESICS | ALGOS PHARMACEUTICAL CORPORATION (US) | 2000-05-25 | — | — | WO | claimed |
| WO-2000029023-A1 | COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | ALGOS PHARMACEUTICAL CORPORATION (US) | 2000-05-25 | — | — | WO | claimed |
| WO-1998050075-A1 | COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | ALGOS PHARMACEUTICAL CORPORATION (US) | 1998-11-12 | — | — | WO | claimed |
| US-5175201-A | VINYL-TERMINATED CARBAMYLMETHYLATED MELAMINES, VINYL-TERMINATED POLYURETHANE/POLYAMIDE POLYMERS AND COATING/ADHESIVE COMPOSITIONS CONTAINING SAME | AMERICAN CYANAMID COMPANY (US) | 1992-12-29 | — | — | US | claimed |
| JP-58145751-A | — | — | None | — | — | JP | disclosed |
| JP-56125307-A | — | — | None | — | — | JP | disclosed |
| US-20260103473-A1 | CITRATE SALT OF CYCLIN-DEPENDENT KINASE (CDK4/6) INHIBITOR, CRYSTAL FORM THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | AVANC PHARMACEUTICAL CO LTD (CN) | 2026-04-16 | — | — | US | disclosed |
| EP-4652167-A1 | GLP-1R AGONISTS AND USES THEREOF | Fochon Biosciences, Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| US-12312349-B2 | Apoptosis-inducing agents | FOCHON PHARMACEUTICALS, LTD. (CN) | 2025-05-27 | — | — | US | disclosed |
| US-4397783-A | HYDRODEHALOGENATION WITH AN ORGANOTIN HYDRIDE | PFIZER INC. (US) | 1983-08-09 | — | — | US | disclosed |
| JP-S56125307-A | FIRST LIQUID FOR PERMANENT WAVE | HOOU KK | 1981-10-01 | — | — | JP | disclosed |
| US-4187338-A | PLASTICIZED POLYVINYL CHLORIDE, SYNTHETIC RUBBER | LONSEAL CORPORATION (JP) | 1980-02-05 | — | — | US | disclosed |
| US-4167415-A | Photocurable composition comprising copolymer of maleic acid monoester and α-olefin compound | KANSAI PAINT CO., LTD. (JP) | 1979-09-11 | — | — | US | disclosed |
| US-4092172-A | Photocurable composition comprising a copolymer of a maleic acid monoester with an α-olefine | KANSAI PAINT CO., LTD. (JA) | 1978-05-30 | — | — | US | disclosed |
| US-4020125-A | HYDROGENATED POLYBUTADIENE-DIOL MODIFIED BY ISOCYANATES AND HYDROXYALKYL ACRYLATES | NIPPON SODA COMPANY LIMITED (JA) | 1977-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12312349-B2 | Apoptosis-inducing agents | BCL2, BAX, BAD | GABRA1 3862/4885GABRB2 2134/4885ACHE 4351/4885 |
| US-20260103473-A1 | CITRATE SALT OF CYCLIN-DEPENDENT KINASE (CDK4/6) INHIBITOR, CRYSTAL FORM THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | CDK4, CDK1, CDK6 | GABRA1 3578/4885GABRB2 3630/4885ACHE 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.